DRSC/TRiP Functional Genomics Resources

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Protein Alignment SRSF9 and CstF64

DIOPT Version :10

Sequence 1:NP_003760.1 Gene:SRSF9 / 8683 HGNCID:10791 Length:221 Species:Homo sapiens
Sequence 2:NP_477453.1 Gene:CstF64 / 42239 FlyBaseID:FBgn0027841 Length:419 Species:Drosophila melanogaster


Alignment Length:127 Identity:35/127 - (27%)
Similarity:57/127 - (44%) Gaps:14/127 - (11%)


- Green bases have known domain annotations that are detailed below.


Human    16 IYVGNLPTDVREKDLEDLFYKYGRIREIELK-NRHGLVP--FAFVRFEDPRDAEDAIYGRNGYDY 77
            ::|||:|.:..|:.|:::|.:.|.:..::|. :|....|  |.|..::|...|..|:...|||:.
  Fly    18 VFVGNIPYEATEEKLKEIFSEVGPVLSLKLVFDRESGKPKGFGFCEYKDQETALSAMRNLNGYEI 82

Human    78 GQCRLRVEFPRTYGGR-------GGWPRGGRNGPPTRRSDFRVL----VSGLPPSGSWQDLK 128
            |...|||:...|...|       .|.......|.|....|...|    |:.|||...::.:|
  Fly    83 GGRTLRVDNACTEKSRMEMQQLLQGPQVENPYGEPCEPEDAPELITKTVASLPPEQMYELMK 144

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SRSF9NP_003760.1 RRM1_SRSF9 15..86 CDD:241042 23/72 (32%)
RRM2_SRSF9 104..186 CDD:410161 8/29 (28%)
Interaction with SAFB1 188..200
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 189..221
CstF64NP_477453.1 RRM_CSTF2_CSTF2T 10..94 CDD:410072 23/75 (31%)
CSTF2_hinge 111..190 CDD:433869 9/34 (26%)
CSTF_C 377..416 CDD:464130
Blue background indicates that the domain is not in the aligned region.

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