Protein Alignment SRSF9 and lark

DIOPT Version :10

• Sequence 1: NP_003760.1
• Gene: SRSF9 / 8683
• HGNCID: 10791
• Length: 221
• Species: Homo sapiens
• Sequence 2: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 66/259 - (25%)
• Similarity: 90/259 - (34%)
• Gaps: 85/259 - (32%)

Human    15 RIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGY---- 75
            :|:||||....|..::.:||.|||.:.|.::...:|     ||..:...|.:|||...||.
  Fly    87 KIFVGNLTDKTRAPEVRELFQKYGTVVECDIVRNYG-----FVHLDCVGDVQDAIKELNGRVVDG 146

Human    76 -------------------DYGQC-------RLRVEFPRTYGGRGGWPRGGRNGP-PTRRSDFRV 113
                               |..||       ....|.||.||..|    |||..| |.....:|.
  Fly   147 QPLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAG----GGREPPSPLSAGGYRD 207

Human   114 LVSGL----PPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTK-FRSH 173
            .:.|.    ||......|:|.:            .||.        .|.:|..|:.:|:: ....
  Fly   208 RMYGRDPYPPPPPPPPFLRDRI------------MDGF--------RDYDYYDRRFEDSRDLYER 252

Human   174 EGETSYIRVYPE-----------RSTSYGYSRSRSGSRGRDS---------PYQSRGSPHYFSP 217
            ..:||.:|.:|.           ..|..|..||.|.|||.|:         |..|.|...|.||
  Fly   253 RYQTSRMRDFPPPPISRREPMPLPPTLSGSLRSCSVSRGYDTMFSRRSPPPPRSSNGMSRYGSP 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF9	NP_003760.1	RRM1_SRSF9	15..86	CDD:241042	24/100 (24%)
		RRM2_SRSF9	104..186	CDD:410161	18/98 (18%)
		Interaction with SAFB1	188..200		5/11 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..221		14/38 (37%)
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	21/69 (30%)
		hnRNP-R-Q	<88..>258	CDD:273732	48/198 (24%)