Protein Alignment SRSF9 and CG12288

DIOPT Version :10

• Sequence 1: NP_003760.1
• Gene: SRSF9 / 8683
• HGNCID: 10791
• Length: 221
• Species: Homo sapiens
• Sequence 2: NP_609822.1
• Gene: CG12288 / 35027
• FlyBaseID: FBgn0032620
• Length: 435
• Species: Drosophila melanogaster
• Alignment Length: 235
• Identity: 52/235 - (22%)
• Similarity: 92/235 - (39%)
• Gaps: 33/235 - (14%)

Human     6 DERG-------GEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPF--------- 54
            ||.|       .|....::|||||.:.:...|..||..||.::.|.|:...|...|
  Fly   140 DEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAG 204

Human    55 ---AFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVS 116
               |:|..|.|..|:.|: ..||.::.:..|||. |.:...:.|..:..:  |..:.:...:.|.
  Fly   205 SLNAYVVLEKPEIAQQAL-ALNGSEFKENHLRVT-PASMAEKFGQAKDKQ--PSDKDAKRTIFVG 265

Human   117 GLPPSGSWQDLKDHMREAGDVCYADVQKD------GVGMVEYLRKEDMEYALR----KLDDTKFR 171
            .|..|.:.:.|::.....|::.|....:|      ||..|.:.:.:.:..||.    .|||....
  Fly   266 SLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALELNQTLLDDRPIN 330

Human   172 SHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGS 211
            ....:...:.....|..:...:.|::.|:.:.....|.|:
  Fly   331 VERYQVKKLGAKQVRDAAAASAASKTSSKTKAKNQNSAGA 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF9	NP_003760.1	RRM1_SRSF9	15..86	CDD:241042	25/82 (30%)
		RRM2_SRSF9	104..186	CDD:410161	16/91 (18%)
		Interaction with SAFB1	188..200		1/11 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..221		4/23 (17%)
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828	24/81 (30%)
		RRM_SF	261..332	CDD:473069	15/70 (21%)