Protein Alignment SRSF9 and Hrb27C

DIOPT Version :10

• Sequence 1: NP_003760.1
• Gene: SRSF9 / 8683
• HGNCID: 10791
• Length: 221
• Species: Homo sapiens
• Sequence 2: NP_476869.1
• Gene: Hrb27C / 33968
• FlyBaseID: FBgn0004838
• Length: 421
• Species: Drosophila melanogaster
• Alignment Length: 233
• Identity: 52/233 - (22%)
• Similarity: 93/233 - (39%)
• Gaps: 55/233 - (23%)

Human     6 DERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIRE-IELKNR-----HGLVPFAFVRFEDPRD 64
            |||     |:::||.|..:..:::|...|.::|.|.: :.:||.     .|   |.||.|.||.:
  Fly     4 DER-----GKLFVGGLSWETTQENLSRYFCRFGDIIDCVVMKNNESGRSRG---FGFVTFADPTN 60

Human    65 AEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGP--------PTRRSDFRVLVSGLPPS 121
            ....:  :||            |.|..||...|:     |        |.:...::|.:.|||.:
  Fly    61 VNHVL--QNG------------PHTLDGRTIDPK-----PCNPRTLQKPKKGGGYKVFLGGLPSN 106

Human   122 GSWQDLKDHMREAGDVCYADVQKD-------GVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSY 179
            .:..||:......|.|....:..|       |.|.:.:..:..:|:    :.:.::.:..|:...
  Fly   107 VTETDLRTFFNRYGKVTEVVIMYDQEKKKSRGFGFLSFEEESSVEH----VTNERYINLNGKQVE 167

Human   180 IRVYPERSTSYGYSRSRS---GSRGRDSPYQSRGSPHY 214
            |:....|..|.|.:.:.|   |:.|:.....|...||:
  Fly   168 IKKAEPRDGSGGQNSNNSTVGGAYGKLGNECSHWGPHH 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SRSF9	NP_003760.1	RRM1_SRSF9	15..86	CDD:241042	18/76 (24%)
		RRM2_SRSF9	104..186	CDD:410161	16/96 (17%)
		Interaction with SAFB1	188..200		4/14 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..221		8/29 (28%)
Hrb27C	NP_476869.1	RRM1_hnRNPA_hnRNPD_like	9..80	CDD:409763	22/87 (25%)
		RRM2_DAZAP1	94..173	CDD:409765	14/82 (17%)