Protein Alignment STX11 and Syx13

DIOPT Version :10

• Sequence 1: XP_011534515.1
• Gene: STX11 / 8676
• HGNCID: 11429
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_524054.1
• Gene: Syx13 / 39485
• FlyBaseID: FBgn0036341
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 256
• Identity: 48/256 - (18%)
• Similarity: 104/256 - (40%)
• Gaps: 50/256 - (19%)

Human    51 EFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSI 115
            ||.|..|||    .|.:.:::              :..|:|.|| .:.:.:.:...:::...::|
  Fly    46 EFMSLSEDI----GHNITAIH--------------SSTKQLEKQ-LKLIGTSKEQPNLREKVHTI 91

Human   116 AKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQR 180
            .....||.:.....|:.::     |..:||.     |..:.|...||..|...:..|:..:.:..
  Fly    92 NTKCNARVQTTSQDLQRLQ-----AVVRHGD-----RQQKLQLEKLTREFHGVVEKYSNLQRRIS 146

Human   181 DNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNE----IESRHRELL 241
            ...:..:|:..:...:.|..:...::.:|.:.:             :|.|.:    ::.|.|::.
  Fly   147 SAMRQTLQQAQQFADQVVETNARAELLQQQRLE-------------QAHLQQEHDMLDDRRRQVE 198

Human   242 RLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTV----DYTGQAKAQVRKAVQYEEK 298
            ::||.|.||:::..|::.||..|...::.||.::::|.    |.|.:.....|....|..|
  Fly   199 QIESDIIDVNQIMTQLSGLVHDQGQQMDFIENSIEQTAANVEDGTSELAKAARSRQSYRRK 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STX11	XP_011534515.1	Syntaxin	69..264	CDD:459942	32/198 (16%)
		SNARE	233..299	CDD:473982	19/70 (27%)
Syx13	NP_524054.1	Syntaxin_2	54..153	CDD:464199	19/127 (15%)
		SNARE_syntaxin7_like	190..249	CDD:277200	16/58 (28%)