Protein Alignment STX11 and Syx7

DIOPT Version :10

• Sequence 1: XP_011534515.1
• Gene: STX11 / 8676
• HGNCID: 11429
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_730632.1
• Gene: Syx7 / 36173
• FlyBaseID: FBgn0267849
• Length: 282
• Species: Drosophila melanogaster
• Alignment Length: 235
• Identity: 55/235 - (23%)
• Similarity: 88/235 - (37%)
• Gaps: 47/235 - (20%)

Human    81 NQL-LVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQH 144
            ||| ...|...|.||..:.:|...:|.:   |||:      ...||..||.|.:|
  Fly    49 NQLNTPQDSPELKKQLHQIMTYTNQLVT---DTNN------QINEVDKCKERHLK---------- 94

Human   145 GPHSAVARISR----AQYNALTLTF---QRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQ 202
                    |.|    .::.|....|   ||...|..:..::|.......|.|.   .|...:|..
  Fly    95 --------IQRDRLVDEFTAALTAFQSVQRKTADIEKTALRQARGDSYNIARP---PGSSRTGSS 148

Human   203 IEDMFEQGKWDVFSENL---------LADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMA 258
            .....:|.....|.:|.         :......:|.|..:|.:.:.:..||:.|..|:|::.::.
  Fly   149 NSSASQQDNNSFFEDNFFNRKSNQQQMQTQMEEQADLQALEEQEQVIRELENNIVGVNEIYKKLG 213

Human   259 VLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK 298
            .||.:|..|::.||..|::|..:..|....:|||..|..|
  Fly   214 ALVYEQGLTVDSIESQVEQTSIFVSQGTENLRKASSYRNK 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STX11	XP_011534515.1	Syntaxin	69..264	CDD:459942	43/199 (22%)
		SNARE	233..299	CDD:473982	20/66 (30%)
Syx7	NP_730632.1	Syntaxin_2	30..123	CDD:464199	25/100 (25%)
		COG5325	<97..276	CDD:227635	36/160 (23%)
		SNARE	188..247	CDD:473982	16/58 (28%)