Protein Alignment CG42514 and SLC46A2

DIOPT Version :10

• Sequence 1: NP_730171.1
• Gene: CG42514 / 8674108
• FlyBaseID: FBgn0260388
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 104/440 - (23%)
• Similarity: 182/440 - (41%)
• Gaps: 74/440 - (16%)

  Fly   107 EFRTKAMLTNAWFLQWENISAHVFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARM 171
            |.:.:..::|.:.:.  |:...:.|::.|..||..|||..||:.:.|.|:| |..|.:.::...:
Human    67 EDQQQRAISNFYIIY--NLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLG-FLLSRLGLLLKVL 128

  Fly   172 TTWPVQNIIYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGS 236
            ..|||: ::|.|...:.|.|...|.::...|..|..||..:|::|:.::|::...|...|.....
Human   129 LDWPVE-VLYGAAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASG 192

  Fly   237 HLFYNVFNQSYADMF--TVNASLLALAIIYTLCALKWQTTPRQRSLREL-------GCCGFW--- 289
            |||..:...|...:.  ..:.|..:.|::|:|..||...:..:.| :||       |..|.:
Human   193 HLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPS-QELPAVDTVSGTVGTYRTL 256

  Fly   290 -GDFFDKQHVKDSLAVLVKPRKGH---RRSFLIILLVSMALYTFQRDEGQYLYMYTLGKFD---- 346
             .|..|:|:     ||...|..|.   .::.:.:|.|...:|.          :..:|..|
Human   257 DPDQLDQQY-----AVGHPPSPGKAKPHKTTIALLFVGAIIYD----------LAVVGTVDVIPL 306

  Fly   347 --------WD--------VSAYSNFKTFKSSAYVIAMLLAVPLMNKILGWRDTTIIFIGTWAHSI 395
                    |:        .:.|:.|         |...|.|.:.::.  :||||:|.||..:...
Human   307 FVLREPLGWNQVQVGYGMAAGYTIF---------ITSFLGVLVFSRC--FRDTTMIMIGMVSFGS 360

  Fly   396 ARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDNAVPFISGVC 460
            ..|...|...|.:.|....|.....|....||:..||::..|..||||.:|.:.......::...
Human   361 GALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTL 425

  Fly   461 YSQLYRRTQNTNHGGNVFILTIATQIAVFVMILCLHIVLGKNSLAVPEVP 510
            |:::|:.|.:. ..|:.|.|   :....|:.|:.:.||..|.   ||..|
Human   426 YNKIYQLTMDM-FVGSCFAL---SSFLSFLAIIPISIVAYKQ---VPLSP 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_SLC46	56..495	CDD:340944	98/423 (23%)
SLC46A2	NP_149040.3	MFS_SLC46A2_TSCOT	19..460	CDD:341008	99/427 (23%)