Protein Alignment CG42514 and SLC46A2

DIOPT Version :9

• Sequence 1: NP_730171.1
• Gene: CG42514 / 8674108
• FlyBaseID: FBgn0260388
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 104/440 - (23%)
• Similarity: 182/440 - (41%)
• Gaps: 74/440 - (16%)

  Fly   107 EFRTKAMLTNAWFLQWENISAHVFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARM 171
            |.:.:..::|.:.:.  |:...:.|::.|..||..|||..||:.:.|.|:| |..|.:.::...:
Human    67 EDQQQRAISNFYIIY--NLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLG-FLLSRLGLLLKVL 128

  Fly   172 TTWPVQNIIYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGS 236
            ..|||: ::|.|...:.|.|...|.::...|..|..||..:|::|:.::|::...|...|.....
Human   129 LDWPVE-VLYGAAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASG 192

  Fly   237 HLFYNVFNQSYADMF--TVNASLLALAIIYTLCALKWQTTPRQRSLREL-------GCCGFW--- 289
            |||..:...|...:.  ..:.|..:.|::|:|..||...:..:.| :||       |..|.:
Human   193 HLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPS-QELPAVDTVSGTVGTYRTL 256

  Fly   290 -GDFFDKQHVKDSLAVLVKPRKGH---RRSFLIILLVSMALYTFQRDEGQYLYMYTLGKFD---- 346
             .|..|:|:     ||...|..|.   .::.:.:|.|...:|.          :..:|..|
Human   257 DPDQLDQQY-----AVGHPPSPGKAKPHKTTIALLFVGAIIYD----------LAVVGTVDVIPL 306

  Fly   347 --------WD--------VSAYSNFKTFKSSAYVIAMLLAVPLMNKILGWRDTTIIFIGTWAHSI 395
                    |:        .:.|:.|         |...|.|.:.::.  :||||:|.||..:...
Human   307 FVLREPLGWNQVQVGYGMAAGYTIF---------ITSFLGVLVFSRC--FRDTTMIMIGMVSFGS 360

  Fly   396 ARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDNAVPFISGVC 460
            ..|...|...|.:.|....|.....|....||:..||::..|..||||.:|.:.......::...
Human   361 GALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTL 425

  Fly   461 YSQLYRRTQNTNHGGNVFILTIATQIAVFVMILCLHIVLGKNSLAVPEVP 510
            |:::|:.|.:. ..|:.|.|   :....|:.|:.:.||..|.   ||..|
Human   426 YNKIYQLTMDM-FVGSCFAL---SSFLSFLAIIPISIVAYKQ---VPLSP 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	87/364 (24%)
		MFS	132..495	CDD:119392	94/398 (24%)
SLC46A2	NP_149040.3	MFS_1	84..421	CDD:284993	87/365 (24%)
		MFS	<282..453	CDD:304372	41/195 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.880