DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42514 and slc46a3

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_009303566.1	Gene:	slc46a3 / 556282	ZFINID:	ZDB-GENE-100105-2	Length:	475	Species:	Danio rerio

Alignment Length:	501	Identity:	113/501 - (22%)
Similarity:	212/501 - (42%)	Gaps:	78/501 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VEPTMFLYMFA-FMITSVVEQ----------NFFLYKS-----CRVNRNFTEEICRNLNKPENEE 107
            :||.:.||.|| ||...:::|          :.|:|.|     |..|.::.     .|::...:|
Zfish     7 IEPAVGLYAFAMFMFYPLLQQYVYRRLWFELSGFIYTSESLSHCSSNHSYI-----TLHQAVQKE 66

  Fly   108 FRTKAMLTNAWFLQWENISAHVFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMT 172
                    .:.||....:...:..:|.||.|.|:||..|||:.::..|||:..::...|:.:|.:
Zfish    67 --------TSLFLLHSELCFLIPSLISALLLVSYSDYCGRKVAIVPPLVGEALHALSYVLVSRFS 123

  Fly   173 TWPVQNIIYSATLPSALTGADVAIFASCFAYISDI--SSLQ-QRTIRVTILDVIYLSAMPMGVAL 234
            .  ..|.:.:::..|.|.|....:...||||::|:  ..|: |:|:|:..||:|      :||..
Zfish   124 F--SLNYLLASSFMSGLMGGPPTLIGGCFAYVADLCGEDLEGQKTVRMARLDMI------LGVLT 180

  Fly   235 G-SHLFYNVFNQS--YADMFTVNASLLALAIIYTLCALK----------------WQTTPRQRSL 280
            | :.|....|.::  :...|.....|..:.::|.|..||                ....||.|..
Zfish   181 GLASLCTGFFIKAAGFTWPFLTAVFLHLINLLYVLVVLKESLVLPNSAVSTSSPSASEAPRLRQT 245

  Fly   281 RELGCCGFWGDFFDKQHVKDSLAVLVKPRKGHRRSFLIILLVSMALYTFQRDEGQYLY-MYTLG- 343
            :.|            ......:.:|.......|...|:::|.:.|.:......|..:: :|.|.
Zfish   246 QAL------------TTRLQGVYLLFAASNRRRNVVLLLMLAAFAFFKLALQGGWSIFILYELNT 298

  Fly   344 KFDWDVSAYSNFKTFKSSAYVIAMLLAVPLMNKILGWRDTTIIFIGTWAHSIARLFFYFATNTDL 408
            ...|. ..:..:.:..|:|..:.....|.|:::.|  .|..||.:|..:.:...:...||..|.|
Zfish   299 PLCWS-EVFVGYGSALSTAIYLVSFAGVALLSRCL--PDAYIILLGLMSVAAGLIMAAFAKTTLL 360

  Fly   409 LYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDNAVPFISGVCYSQLYRRTQNTNH 473
            ::...:...|..:..|::|:|.||||..||:|.:||.::..:.....:|...::.:|..|.:...
Zfish   361 MFLVRLPLLLSIMPTPVLRSMMSKIVSGSEQGAMFACVAFVEMLSVGVSFTVFNSIYAATLSWFS 425

  Fly   474 GGNVFILTIATQI--AVFVMILCLHIVLGKNSLAVPEVPEKESGLI 517
            |.:..:....|.|  |:..:||||.:.:.:.|:.:.|..|..:.::
Zfish   426 GFSFLLAAGLTVIPSALICVILCLRLDVYEESIKLTESMENHTEIL 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	81/352 (23%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	90/388 (23%)
slc46a3	XP_009303566.1	MFS_1	77..409	CDD:284993	81/354 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6513
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.830