Protein Alignment CG42514 and Slc46a1

DIOPT Version :9

• Sequence 1: NP_730171.1
• Gene: CG42514 / 8674108
• FlyBaseID: FBgn0260388
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_081016.2
• Gene: Slc46a1 / 52466
• MGIID: 1098733
• Length: 459
• Species: Mus musculus
• Alignment Length: 453
• Identity: 116/453 - (25%)
• Similarity: 199/453 - (43%)
• Gaps: 68/453 - (15%)

  Fly    59 VEPTMFLYMFAFMITSVVEQNFFLYK-SCRVNRNFT--EEICRNLN-KPENEEFRTKAMLTNAWF 119
            |||.:||..||.::...:...:..:: |..:..|.|  .|.|.|.: .|..:|..|   ||:.|.
Mouse    25 VEPLVFLANFALVLQGPLTTQYLWHRFSTELGYNGTRHRENCGNQSADPLMKEVET---LTSHWT 86

  Fly   120 LQWENISAHVFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQ-----NI 179
            | :.|:...:..:..:..||::|||.||:..|::..:|       :::.|.::.:.||     ..
Mouse    87 L-YMNVGGFLVGLFWSTLLGAWSDRVGRRPLLVLASLG-------LLLQAVVSIFVVQLELHVGF 143

  Fly   180 IYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGSHLFYNVFN 244
            ........||.|....:.|:.||.::|:||...||.|:.:|:.....|..:...||.|.   :..
Mouse   144 FVLGRALCALLGDFNGLLAASFASVADVSSNHSRTFRMALLEACIGVAGTLASLLGGHW---LRA 205

  Fly   245 QSYADMFTVNASLLALAIIYTLCALKWQTTPRQRSLRELGCCGFWGDFFDKQHVKDSLAVLVKPR 309
            |.||:.|.:..:||.:..:|..... .:|....:|.|          .|..:|.:....:.|.|
Mouse   206 QGYANPFWLALALLIVMALYAAFCF-GETVKEPKSTR----------LFTLRHHRSIARLYVVP- 258

  Fly   310 KGHRRSFLIILLVSMALY---TFQRDEGQYLYMYTL-GKFDWDVSAYSNFKTFKSSAYVIAMLLA 370
             ...:|.:.:.|.|:|::   |........|.:|.| ....||    |....:.|:|.      .
Mouse   259 -APEKSRMHLALYSLAIFVVVTVHFGAQDILTLYELSAPLCWD----SKLIGYGSAAQ------H 312

  Fly   371 VPLMNKILGWR-------DTTIIFIGTWAHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRA 428
            :|.:..:||.|       ||.:..||...:.:..:.|.|||.|.|::.|..:..|..:..|:|||
Mouse   313 LPYLTSLLGLRLLQFCLADTWVAEIGLAFNILGMVVFAFATITPLMFTGYGLLFLSLVTTPVIRA 377

  Fly   429 MTSKIVPTSERGKVFALLSVCDNAVPFI--SGVCYSQLYRRTQNTNHG-------GNVFILTI 482
            ..||:|..||:|.:|:.:: |.|::..:  ||: ::.:|..|.|...|       |.:||..|
Mouse   378 KLSKLVSESEQGALFSAVA-CVNSLAMLMASGI-FNSIYPATLNFMKGFPFLLGAGLLFIPAI 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	85/346 (25%)
		MFS	132..495	CDD:119392	95/376 (25%)
Slc46a1	NP_081016.2	MFS	73..443	CDD:119392	103/405 (25%)
		MFS_1	94..407	CDD:284993	85/346 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I9497
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8701
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.860