DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42514 and CG17637

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_649237.1	Gene:	CG17637 / 40275	FlyBaseID:	FBgn0037004	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	530	Identity:	94/530 - (17%)
Similarity:	203/530 - (38%)	Gaps:	132/530 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 WHVVKSTSVEPTMFLYMFAFMITSVVEQNFFLYKSCRVNRNFTEEICRNLNKPENEEFRTKAMLT 115
            ||.|..|      |::.|::.:.:|               .|.|::        :..|..:.:|.
  Fly    26 WHAVIVT------FMHYFSWGLLTV---------------PFIEKL--------SGSFGNRVLLV 61

  Fly   116 NAWFLQWENISAHV-FPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQNI 179
            :........|...| .|:     :|:.||..|||:.:|:.:...:.....:::.   :.|
  Fly    62 DGLVYGVRGILGFVTTPV-----MGAISDFHGRKVVMLLAVATTYAPIPFMMLK---SWW----- 113

  Fly   180 IYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGSHLFYNVFN 244
            .::....|::.|   :.::|..||::|.::::.|:.....:...:.:.:....:||::|..:..:
  Fly   114 FFAILTVSSICG---STYSSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGS 175

  Fly   245 QSYADMFTVNASLLALAIIYTL---CALKWQ-------------------TTPRQR--------- 278
            .|...:.|:...:..|.||:.:   ..||.:                   .:|:::
  Fly   176 ASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGK 240

  Fly   279 -----------------------SLRELGCCGFWGDFFDKQHV-------KDSLAVLVKPRKGHR 313
                                   |..|    ....|..:|:.:       .|...||.|.||.
  Fly   241 VNVEVNKPTSQNIVTNKELDQQFSKEE----NLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKD-- 299

  Fly   314 RSFLIILLVS-MALYTFQR-DEGQYLYMYTLGKFDWDVSAYSNFKTFKSSAYVIAMLLAVPLMNK 376
            ::.|:|.|:: ::::.|.. |....:|:.|...|:::  ..|......|...:.:.:|...:||
  Fly   300 KNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYE--EVSMMLGLLSVLAITSNILLGYIMN- 361

  Fly   377 ILG--WRDTTIIFIGTWAHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSER 439
            |:|  |.    |.:|.....:..|||.|.|:..:.:..:::.:|..|:.....|:.|.......|
  Fly   362 IVGAKWS----IRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNR 422

  Fly   440 GKVFALLS----VCDNAVPFISGVCYSQLYRRTQNTNHGGN--VFILTIATQIAVFVMILCLHIV 498
            |.|..::|    :.:...|...|:.:. :::....|:...|  :.:..:.:.|:|||.|: |...
  Fly   423 GAVLGIISGIECLSEGVGPAFFGLLFF-IFQDDSETDLKVNSPISMPFVISAISVFVAIV-LSSF 485

  Fly   499 LGKNSLAVPE 508
            :.|::|...|
  Fly   486 IKKDTLGNEE 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	70/398 (18%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	76/433 (18%)
CG17637	NP_649237.1	MFS	25..487	CDD:119392	91/520 (18%)
CG17637	NP_649237.1	MFS_1	30..441	CDD:284993	78/468 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840