DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42514 and Mfsd14b

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001100804.1	Gene:	Mfsd14b / 306687	RGDID:	1308377	Length:	507	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	78/392 - (19%)
Similarity:	157/392 - (40%)	Gaps:	106/392 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 TKAMLTNAWFLQWENISAHVF-------------PIILALFLGSFSDRRGRKLPLLMGLVGKFFY 161
            |..|||    :..|....|.|             ..:.|..:|:.||..||| |.|:|.|   |:
  Rat    65 TTPMLT----VLHETFPQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRK-PFLLGTV---FF 121

  Fly   162 STMIVVNARMTTWPVQNIIYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLS 226
            :...:...|::.|....:|       :::|.....|:..|||::|.:...:|:.....:...:.:
  Rat   122 TCFPIPLMRISPWWYFGMI-------SVSGVFSVTFSVIFAYVADFTQEHERSTAYGWVSATFAA 179

  Fly   227 AMPMGVALGSHLFYNVFNQSYADMFTV-NASLLALA-IIYTLCA-----------------LKWQ 272
            ::....|:|::|     :.:|.|...| .|:::||. |.:.|.|                 :.|:
  Rat   180 SLVSSPAIGTYL-----SSNYGDSLVVLVATVVALLDICFILVAVPESLPEKIRPASWGAQISWK 239

  Fly   273 TTPRQRSLRELGCCGFWGDFFDKQHVKDSLAVLVKPRKGHRRSFLIILLVSMALY-TFQRDEGQY 336
            ......||:::|              |||                .:||:.:.:: ::..:.|||
  Rat   240 QADPFASLKKVG--------------KDS----------------TVLLICITVFLSYLPEAGQY 274

  Fly   337 --LYMYTLGKFDWDVSAYSNFK--TFKSSAYVIAMLLAVPLMNKI---LGWRDTTIIFIGTWAHS 394
              .::|..     .|..:.:.|  .|.:...::::|.....::|:   ||.::|.::.:|   ..
  Rat   275 SSFFLYLR-----QVIGFGSVKIVAFIAMVGILSILAQTVFLSKLMRSLGNKNTVLLGLG---FQ 331

  Fly   395 IARLFFY-FATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDNAVPFISG 458
            |.:|.:| |.....:::|...|.::..|..|.:.|:.|:...:.::|       |....:..|.|
  Rat   332 ILQLAWYGFGAQAWMMWAAGTVAAMSSITFPAVSALISRNAESDQQG-------VAQGIITGIRG 389

  Fly   459 VC 460
            :|
  Rat   390 LC 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	70/369 (19%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	71/357 (20%)
Mfsd14b	NP_001100804.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		MFS_MFSD14	47..452	CDD:340945	78/392 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	462..483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D763423at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820