DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42514 and SPAC14C4.07

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_594912.1	Gene:	SPAC14C4.07 / 2541546	PomBaseID:	SPAC14C4.07	Length:	644	Species:	Schizosaccharomyces pombe

Alignment Length:	615	Identity:	103/615 - (16%)
Similarity:	201/615 - (32%)	Gaps:	169/615 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TGAHSENAAQRRNSRSSENSED----NENSASGTVREQRDEAAGRTVLQWAWHVVKSTSVEPTMF 64
            :.:|....|:.:|..|:.||.:    ||..:|.:..............:   .:.:..|:.|.:.
pombe    70 SSSHDSFKAKPKNYDSTSNSNEPISFNEPDSSNSHHNNESICNNDNCCR---EIARRRSLSPLLI 131

  Fly    65 L---YMFAFMITSVVEQNFFLYKS--CRVNRNF-------TEEICRNLNKPENEEFRTKAMLTNA 117
            |   ::.||....:.....||.:.  |.::.|.       .:.|||      ..|..|......|
pombe   132 LPLNFINAFSWGMIEIPLLFLLRQELCAIHYNLDPTQLSPDDPICR------LAEITTGVSKVRA 190

  Fly   118 WFLQWENISAHVFPIILALFLGSFS--------DRRGRKLPLLMGLVGKFFYSTMIVVNARMTTW 174
            .|..            ||.|||.||        |..||:|.|.:.:.........::..:.....
pombe   191 AFGS------------LAAFLGLFSTAYYGTMGDIYGRRLVLFITVSFLLLGDLWLLYQSYAPKH 243

  Fly   175 PVQNIIYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALG---- 235
            | ..::::|.| ..|.|....:.||..::::|.|..:   .|...|.:.: :|..:|.|||
pombe   244 P-YFVLFAAAL-KGLGGYISTVVASQNSFVADCSKTE---FRAWYLGLNF-AAYHLGTALGPSLS 302

  Fly   236 -------SHLFYNVFNQSYADMFTVNASLLALAIIYTLCALKWQTTPRQRSLRE--------LGC 285
                   .|::|         :|.:.::...:.::|.     |...|....:.|        .|.
pombe   303 GFIVQYTPHMYY---------VFYITSTFWIIYLLYV-----WLILPESLDVSESKEQQNKISGF 353

  Fly   286 CGFWGDFFDKQHVKDSLAVLVKPRK--------------------GHRRSFLIILLVSMALYTFQ 330
            ...|....:.       .:::.||.                    |.|...:::..:.::|....
pombe   354 SSIWRSCLEP-------LIILWPRSLCTEESCEFHQYDINADTHAGRRHWDVLLAAILISLTLLG 411

  Fly   331 RDEGQYLYMYTLGKFDWDVSAYSNFKTFKSSAYVIAMLLAVPLMNKIL----------------- 378
            ......|.:||..||.|.....|...:..|.|..|.::...||::|::
pombe   412 AGSMGLLPLYTDYKFGWGPMKASLILSTDSFASSITLVALFPLLSKVIEKIIEKLYSSEGLFEDP 476

  Fly   379 ----------GWRDT------------------------TIIFIGTWAHSI-------ARLFFYF 402
                      |.|:.                        ||:....|...:       |.:....
pombe   477 SRADNTSSLQGIRNVFSYLVRPGYSRSSILRGRTADEKYTIVKRDVWNAQLGYAIALSAAVLLAV 541

  Fly   403 ATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDNAVPFISGVCYSQLYRR 467
            |.:...|:...::.::..:|.|.::::....|.:...|:|.|..:|.:.....|.|..|:.:|..
pombe   542 AKSDVALFTAVIIQAISNMVVPCVQSIALNGVQSEYNGRVLAAFAVFEAVALIIRGPIYAFVYTE 606

  Fly   468 TQNTNHGGNVFILTIATQIAVFVMILCLHI 497
            :...::...:|.|:.......|::|..:.:
pombe   607 SMKVSYPNMIFFLSAVIYGCCFIIIFFMRL 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	71/433 (16%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	78/467 (17%)
SPAC14C4.07	NP_594912.1	MFS	190..>335	CDD:119392	35/176 (20%)
SPAC14C4.07	NP_594912.1	MFS_1	194..459	CDD:284993	55/303 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.940