DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42514 and acy-4

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_504486.4	Gene:	acy-4 / 178949	WormBaseID:	WBGene00000071	Length:	1013	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	55/287 - (19%)
Similarity:	87/287 - (30%)	Gaps:	101/287 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 YKSCRVNRNFTEEICRNLNKPENEEFRTKAMLTNAWFLQWENISAHV--FPIILALFLG-SFSDR 144
            ||..||...|..                         |::::|...|  :..|:|:.:| .|.
Worm   564 YKQVRVENKFVR-------------------------LKYKDIPFQVTLYVAIVAICIGIKFG-- 601

  Fly   145 RGRKLPLLMGLVGKFFYSTM-IVVNARMTTWPVQNIIYSATLPSALTGADVAIFASCFAYISDIS 208
                   ||.||...|...| ||:.:.|.....:.:|..|.|.|.:.|.       .|..:|
Worm   602 -------LMNLVSFSFVPQMFIVLTSVMIFILTRALIKHARLVSLVIGV-------LFILLS--- 649

  Fly   209 SLQQRTIRVTILDVIYLSAMPMGVALGSHLFYNVFNQSYADMFTVNASLLALAIIYTLCALKWQT 273
                  |::.||..:|.|.....|.       ..|..:|.|.|.          |:.:|.|
Worm   650 ------IQIVILMGMYESKFTCDVE-------KCFKNNYTDFFE----------IFEICTL---- 687

  Fly   274 TPRQRSLRELGCCGFWGDFFDKQHVK----DSLAVLVKPR----------KGHRRSFLIILLVSM 324
                     ..|.....||..|..:.    .|..||:..:          .....:|.::..:::
Worm   688 ---------ATCVILSVDFMTKLLMSMIYFSSFTVLITAKLIRINQYEALLSTYANFCVLSCLTL 743

  Fly   325 ALYTFQRDEGQYLYMYTLGKFDWDVSA 351
            .|..|.....:.:..|   .|.|.:.|
Worm   744 LLVVFSTRRSELISRY---DFIWKLQA 767

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	48/241 (20%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	47/236 (20%)
acy-4	NP_504486.4	AC_N	<50..291	CDD:292831
		CYCc	260..451	CDD:214485
		Guanylate_cyc	293..448	CDD:278633
		CYCc	778..984	CDD:214485
		Guanylate_cyc	807..1003	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4862
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950