DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42514 and LOC100487203

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_002936740.3	Gene:	LOC100487203 / 100487203	-ID:	-	Length:	449	Species:	Xenopus tropicalis

Alignment Length:	468	Identity:	110/468 - (23%)
Similarity:	199/468 - (42%)	Gaps:	61/468 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 VVKSTSVEPTMFLYMFAFMITSVVEQNFFLYKSCRVNRNFTEEICRNLNKPENEEFRTKAMLTNA 117
            |:..|.:||.        :..:.|..:|:........:|:..:...:.|...:|..: ||:  :.
Frog     2 VMVRTWIEPV--------VAGAQVASSFYDTGLLMTVKNYYNQTINSSNISSDEALQ-KAI--SN 55

  Fly   118 WFLQWENISAHVFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQNIIYS 182
            :::.:.:|.. :.|::.|.||...||:..||:.:.:.|.| :..|.|.::...:..||::.:..|
Frog    56 FYIVYNSIMG-LGPLLSAYFLAKISDKINRKITICVPLTG-YLISRMFLLFVILWDWPIEVMFGS 118

  Fly   183 ATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGSHLF--YNVFNQ 245
            |.| :.|||...|.:|...|:.|..|:..:|:|::.|::::|..|...|.....|:|  .|:.:.
Frog   119 AAL-NGLTGWFTAYWAGVMAWASLASTESKRSIKLIIIELVYGLAGFAGSLASGHIFVHININHH 182

  Fly   246 SYADMFTVNASLLALAIIYTLCALKWQTTPRQRSLRELGCCGF-WGDFFDKQHVKD--------- 300
            ..|.:.:.:.......::|:...||..:.       |.||... .|...::...:|
Frog   183 QGAILASCSLGCYVFCVLYSTFVLKIPSP-------ETGCIETNEGTTINETKKEDSEYTERSRL 240

  Fly   301 ----SLAVLVKPRKGHRRSFLIILLVSMALYTFQRDEGQ-YLYMYTLGK-FDW--------DVSA 351
                ||..|.:|.:...:..||.:.:|:.||.......: .:.::.|.| ..|        :.:.
Frog   241 LGDKSLQTLNQPHQRTTKFILISIFISVILYNIAAGGAEDVINVFVLKKPLSWGPVDVGYGNAAT 305

  Fly   352 YSNFKTFKSSAYVIAMLLAVPLMNKILGWRDTTIIFIGTWAHSIARLFFYFATNTDLLYAGAVVC 416
            |.|:.|.....||.:|.:.           |..:|.||..:.|...|...|...|.|.|....|.
Frog   306 YINYITSFLGVYVFSMCVG-----------DLGLIIIGMISFSCGILIMAFVQWTYLYYVARAVM 359

  Fly   417 SLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDNAVPFISGVCYSQLYRRTQNTNHGGNVFIL- 480
            ....|..|:||::.||.|..|..|||||:|.:....|...|....::||:.|.:. :.|..|:|
Frog   360 MFSLIPTPIIRSLISKHVQESLYGKVFAVLQLAIGVVYVSSSAGLNKLYQATLDW-YSGFCFLLF 423

  Fly   481 -TIATQIAVFVMI 492
             |:....|:.|:|
Frog   424 STLGFLSAIPVII 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	87/354 (25%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	97/389 (25%)
LOC100487203	XP_002936740.3	MFS_SLC46A2_TSCOT	5..438	CDD:341008	109/465 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I8288
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I4968
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47543
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.070