DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CanA-14F and PPT1

DIOPT Version :9

Sequence 1:	NP_001245717.1	Gene:	CanA-14F / 8674098	FlyBaseID:	FBgn0267912	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	325	Identity:	116/325 - (35%)
Similarity:	167/325 - (51%)	Gaps:	45/325 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 LKQHFI--------LEGR-IEESAALRIIQEGATLLRTEKTMIDIE------APVTVCGDIHGQF 169
            :.|.||        |:|: :.:.....||....||.|.|.:|:::|      ..::||||.||||
Yeast   190 MSQEFISKMVNDLFLKGKYLPKKYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQF 254

  Fly   170 YDLMKLFEIGG--SPATTKYLFLGDYVDRGYFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTE 232
            ||::.||...|  .|..| |||.||:||||.:|.|..|..:.|||.:|...||.|||||..::.:
Yeast   255 YDVLNLFRKFGKVGPKHT-YLFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNK 318

  Fly   233 YFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEIHELEDIRRLDRFKEPP 296
            .:.|:.|||.|||:|:::....:|:.||||.|:|..:|.:|||| |.....|.|.:.:|||.:||
Yeast   319 IYGFEDECKYKYSQRIFNMFAQSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQPP 383

  Fly   297 AFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAG 361
            ..|...:|||:||.|..|        ...|.||..:.:.......||:||.|..|.|:||.:..|
Yeast   384 RDGAFMELLWADPQEANG--------MGPSQRGLGHAFGPDITDRFLRNNKLRKIFRSHELRMGG 440

  Fly   362 YRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVL------------KYENNVMNIRQFNCSPHP 414
            .:..:|.:      |:|:||||||.|...|...|:            :.::..:.|..|....||
Yeast   441 VQFEQKGK------LMTVFSAPNYCDSQGNLGGVIHVVPGHGILQAGRNDDQNLIIETFEAVEHP 499

Fly 415 414
Yeast 500 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CanA-14F	NP_001245717.1	MPP_PP2B	115..419	CDD:277361	116/325 (36%)
CanA-14F	NP_001245717.1	PP2Ac	132..403	CDD:197547	107/291 (37%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	116/325 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810