Protein Alignment CanA-14F and PPP3CB

DIOPT Version :10

• Sequence 1: NP_727985.2
• Gene: CanA-14F / 8674098
• FlyBaseID: FBgn0267912
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: XP_047281382.1
• Gene: PPP3CB / 5532
• HGNCID: 9315
• Length: 534
• Species: Homo sapiens
• Alignment Length: 514
• Identity: 388/514 - (75%)
• Similarity: 434/514 - (84%)
• Gaps: 28/514 - (5%)

  Fly    88 ERVIDSVAFPPSRKLTCADVFDARTGKPQHDVLKQHFILEGRIEESAALRIIQEGATLLRTEKTM 152
            :||:.:|.|||:.:||..:|||. .|.|:.||||.|.:.|||::|..|||||.|||.:||.||||
Human    24 DRVVKAVPFPPTHRLTSEEVFDL-DGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTM 87

  Fly   153 IDIEAPVTVCGDIHGQFYDLMKLFEIGGSPATTKYLFLGDYVDRGYFSIECVLYLWSLKITYPQT 217
            |::|||:||||||||||:|||||||:|||||.|:||||||||||||||||||||||.|||.||.|
Human    88 IEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPST 152

  Fly   218 LFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIHE 282
            ||||||||||||||||||||||||||||||||:|||:|||.||||||:||||||||||||||||.
Human   153 LFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHT 217

  Fly   283 LEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAACCDFLQNNN 347
            |:|||||||||||||||||||||||||.|||||||:.:.::||:||||||||:|.|.|:||||||
Human   218 LDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNN 282

  Fly   348 LLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSP 412
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   283 LLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSP 347

  Fly   413 HPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELMTEESEEPLSDDE-----------AA 466
            |||||||||||||||||||||||||||||||:||||||||||..::   .||           ||
Human   348 HPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQ---FDERLIYGNKKVGSAA 409

  Fly   467 LRKEVIRNKIRAIGKMARVFSVLREESESVLQLKGLTPTGALPLGALSGGKQSLKN--------- 522
            .|||:||||||||||||||||||||||||||.||||||||.||.|.|:||:|:|::
Human   410 ARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAE 474

  Fly   523 -AMQGFSPNHKITSFAEAKGLDAVNERMPPRRDATPSPAEEGQKSLSAAAAAAANANAN 580
             |::||||.|:|.||.||||||.:|||||||:||.   .::|..||:.|.|...:...|
Human   475 KAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAV---QQDGFNSLNTAHATENHGTGN 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CanA-14F	NP_727985.2	MPP_PP2B	115..419	CDD:277361	261/303 (86%)
PPP3CB	XP_047281382.1	MPP_PP2B	50..354	CDD:277361	261/303 (86%)