Protein Alignment CanA-14F and PPP2CB

DIOPT Version :10

• Sequence 1: NP_727985.2
• Gene: CanA-14F / 8674098
• FlyBaseID: FBgn0267912
• Length: 584
• Species: Drosophila melanogaster
• Sequence 2: NP_001009552.1
• Gene: PPP2CB / 5516
• HGNCID: 9300
• Length: 309
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 120/286 - (41%)
• Similarity: 168/286 - (58%)
• Gaps: 16/286 - (5%)

  Fly   129 RIEESAALRIIQEGATLLRTEKTMIDIEAPVTVCGDIHGQFYDLMKLFEIGGSPATTKYLFLGDY 193
            ::.|:....:.::...:|..|..:.::..|||||||:||||:|||:||.|||....|.|||:|||
Human    22 QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDY 86

  Fly   194 VDRGYFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYDACMDAFD 257
            |||||:|:|.|..|.:||:.||:.:.:||||||.|.:|:.:.|..||..|| :..|:....|.||
Human    87 VDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFD 151

  Fly   258 CLPLAALMNQQFLCVHGGLSPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFY 322
            .|||.||::.|..|:||||||.|..|:.||.|||.:|.|..||||||||||| :|.|.
Human   152 YLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP-DDRGG------- 208

  Fly   323 THNSVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLD 387
            ...|.||..|.:.......|...|.|..:.|||:....||......      :::||||||||..
Human   209 WGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDR------NVVTIFSAPNYCY 267

  Fly   388 VYNNKAAVLKYENNV-MNIRQFNCSP 412
            ...|:||:::.::.: .:..||:.:|
Human   268 RCGNQAAIMELDDTLKYSFLQFDPAP 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CanA-14F	NP_727985.2	MPP_PP2B	115..419	CDD:277361	120/286 (42%)
PPP2CB	NP_001009552.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	119/284 (42%)