DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CanA-14F and PPP2CA

DIOPT Version :9

Sequence 1:NP_001245717.1 Gene:CanA-14F / 8674098 FlyBaseID:FBgn0267912 Length:584 Species:Drosophila melanogaster
Sequence 2:NP_002706.1 Gene:PPP2CA / 5515 HGNCID:9299 Length:309 Species:Homo sapiens


Alignment Length:286 Identity:120/286 - (41%)
Similarity:167/286 - (58%) Gaps:16/286 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   129 RIEESAALRIIQEGATLLRTEKTMIDIEAPVTVCGDIHGQFYDLMKLFEIGGSPATTKYLFLGDY 193
            ::.||....:.::...:|..|..:.::..|||||||:||||:|||:||.|||....|.|||:|||
Human    22 QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDY 86

  Fly   194 VDRGYFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKY-SERVYDACMDAFD 257
            |||||:|:|.|..|.:||:.|.:.:.:||||||.|.:|:.:.|..||..|| :..|:....|.||
Human    87 VDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFD 151

  Fly   258 CLPLAALMNQQFLCVHGGLSPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFY 322
            .|||.||::.|..|:||||||.|..|:.||.|||.:|.|..||||||||||| :|.|.       
Human   152 YLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP-DDRGG------- 208

  Fly   323 THNSVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLD 387
            ...|.||..|.:.......|...|.|..:.|||:....||......      :::||||||||..
Human   209 WGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDR------NVVTIFSAPNYCY 267

  Fly   388 VYNNKAAVLKYENNV-MNIRQFNCSP 412
            ...|:||:::.::.: .:..||:.:|
Human   268 RCGNQAAIMELDDTLKYSFLQFDPAP 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CanA-14FNP_001245717.1 MPP_PP2B 115..419 CDD:277361 120/286 (42%)
PP2Ac 132..403 CDD:197547 117/272 (43%)
PPP2CANP_002706.1 MPP_PP2A_PP4_PP6 9..293 CDD:277360 119/284 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53795
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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