DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CanA-14F and Pp2B-14D

DIOPT Version :9

Sequence 1:	NP_001245717.1	Gene:	CanA-14F / 8674098	FlyBaseID:	FBgn0267912	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_001245715.1	Gene:	Pp2B-14D / 32624	FlyBaseID:	FBgn0011826	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	560	Identity:	477/560 - (85%)
Similarity:	505/560 - (90%)	Gaps:	14/560 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SSSSQSQSAAQQQQQQN-------QKANVNNTHDNKNAAATTGTAAGSGSGGAAGSAGTQQQGQG 67
            ||::||.|.||......       :..:.|:|..|.|..:::..|||:.|..::.:.||
  Fly     2 SSNNQSSSVAQAATSARTVSAGSAEATDANSTASNNNNNSSSTAAAGNNSDNSSPTTGT------ 60

  Fly    68 GTGTSSGPSSPTKRSTISTKERVIDSVAFPPSRKLTCADVFDARTGKPQHDVLKQHFILEGRIEE 132
            |||.|:| ......:.::|||||:|||.||||.|||.|:|||.|||||.|::|||||||||||||
  Fly    61 GTGASTG-KLHGGHTAVNTKERVVDSVPFPPSHKLTLAEVFDQRTGKPNHELLKQHFILEGRIEE 124

  Fly   133 SAALRIIQEGATLLRTEKTMIDIEAPVTVCGDIHGQFYDLMKLFEIGGSPATTKYLFLGDYVDRG 197
            :.||:|||:||.|||.|||||||||||||||||||||||||||||:|||||:|||||||||||||
  Fly   125 APALKIIQDGAALLRQEKTMIDIEAPVTVCGDIHGQFYDLMKLFEVGGSPASTKYLFLGDYVDRG 189

  Fly   198 YFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLA 262
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   190 YFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLA 254

  Fly   263 ALMNQQFLCVHGGLSPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSV 327
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   255 ALMNQQFLCVHGGLSPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSV 319

  Fly   328 RGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNK 392
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   320 RGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNK 384

  Fly   393 AAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELMTEESE 457
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   385 AAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELMTEESE 449

  Fly   458 EPLSDDEAALRKEVIRNKIRAIGKMARVFSVLREESESVLQLKGLTPTGALPLGALSGGKQSLKN 522
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   450 EPLSDDEAALRKEVIRNKIRAIGKMARVFSVLREESESVLQLKGLTPTGALPLGALSGGKQSLKN 514

  Fly   523 AMQGFSPNHKITSFAEAKGLDAVNERMPPRRDATPSPAEE 562
            ||||||||||||||||||||||||||||||||..|:|:|:
  Fly   515 AMQGFSPNHKITSFAEAKGLDAVNERMPPRRDQPPTPSED 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CanA-14F	NP_001245717.1	MPP_PP2B	115..419	CDD:277361	292/303 (96%)
CanA-14F	NP_001245717.1	PP2Ac	132..403	CDD:197547	262/270 (97%)
Pp2B-14D	NP_001245715.1	MPP_PP2B	107..411	CDD:277361	292/303 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440202
Domainoid	1	1.000	402	1.000	Domainoid score	I693
eggNOG	1	0.900	-	-		E1_COG0639
Homologene	1	1.000	-	-		H55497
Inparanoid	1	1.050	807	1.000	Inparanoid score	I469
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D194337at33208
OrthoFinder	1	1.000	-	-		FOG0000983
OrthoInspector	1	1.000	-	-		mtm6407
orthoMCL	1	0.900	-	-		OOG6_100566
Panther	1	1.100	-	-	P	PTHR45673
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R954
SonicParanoid	1	1.000	-	-		X576
	13	12.830