DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CanA-14F and Ppp1ca

DIOPT Version :9

Sequence 1:	NP_001245717.1	Gene:	CanA-14F / 8674098	FlyBaseID:	FBgn0267912	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_113715.1	Gene:	Ppp1ca / 24668	RGDID:	3375	Length:	330	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	120/329 - (36%)
Similarity:	186/329 - (56%)	Gaps:	38/329 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 ISTKERV-IDSVAFPPSRKLTCADVFDARTGKPQHDVLKQHFILEGRIEESAALRIIQEGATLLR 147
            :|..|:: :||:.   .|.|   :|..:|.||            ..::.|:....:..:...:..
  Rat     1 MSDSEKLNLDSII---GRLL---EVQGSRPGK------------NVQLTENEIRGLCLKSREIFL 47

  Fly   148 TEKTMIDIEAPVTVCGDIHGQFYDLMKLFEIGGSPATTKYLFLGDYVDRGYFSIECVLYLWSLKI 212
            ::..::::|||:.:|||||||:|||::|||.||.|..:.|||||||||||..|:|.:..|.:.||
  Rat    48 SQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKI 112

  Fly   213 TYPQTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLS 277
            .||:..|||||||||..:...:.|..|||.:|:.:::....|.|:|||:||:::::..|.|||||
  Rat   113 KYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLS 177

  Fly   278 PEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAACCDF 342
            |::..:|.|||:.|..:.|..|.:||||||||.:|......:|       ||.|:.:.......|
  Rat   178 PDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGEND-------RGVSFTFGAEVVAKF 235

  Fly   343 LQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQ 407
            |..::|..|.|||:..:.||..:.|.|      |:|:||||||...::|..|::..:..:|
  Rat   236 LHKHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM---- 290

  Fly   408 FNCS 411
              ||
  Rat   291 --CS 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CanA-14F	NP_001245717.1	MPP_PP2B	115..419	CDD:277361	110/297 (37%)
CanA-14F	NP_001245717.1	PP2Ac	132..403	CDD:197547	107/270 (40%)
Ppp1ca	NP_113715.1	MPP_PP1_PPKL	8..298	CDD:277359	118/322 (37%)
Ppp1ca	NP_113715.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820