DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CanA-14F and Ppp3cc

DIOPT Version :9

Sequence 1:	NP_001245717.1	Gene:	CanA-14F / 8674098	FlyBaseID:	FBgn0267912	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	XP_008769035.1	Gene:	Ppp3cc / 171378	RGDID:	621616	Length:	515	Species:	Rattus norvegicus

Alignment Length:	514	Identity:	370/514 - (71%)
Similarity:	435/514 - (84%)	Gaps:	28/514 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 KRSTISTKERVIDSVAFPPSRKLTCADVFDARTGKPQHDVLKQHFILEGRIEESAALRIIQEGAT 144
            :|...||.||||.:|.|||:|:||..:||:  .|||:.||||.|.:.|||:||..||:||.:||.
  Rat     4 RRPQFSTTERVIKAVPFPPTRRLTLKEVFE--NGKPKMDVLKNHLVKEGRVEEDVALKIINDGAA 66

  Fly   145 LLRTEKTMIDIEAPVTVCGDIHGQFYDLMKLFEIGGSPATTKYLFLGDYVDRGYFSIECVLYLWS 209
            :|:.||||:::|||:|||||:||||:|||||||:||||:.|:|||||||||||||||||||||||
  Rat    67 ILKQEKTMLEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWS 131

  Fly   210 LKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHG 274
            |||.:|:||||||||||||||||||||||||:|||||.||:|||..|||||||||:|||||||||
  Rat   132 LKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSELVYEACMHTFDCLPLAALLNQQFLCVHG 196

  Fly   275 GLSPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAAC 339
            |:||||..|:|||:||||.|||||||:|||||||||||:|:||..:.||||:|||||||:||.|.
  Rat   197 GMSPEITCLDDIRKLDRFAEPPAFGPVCDLLWSDPLEDYGSEKTLEHYTHNTVRGCSYFFSYPAV 261

  Fly   340 CDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMN 404
            |:|||||:||||||||||||||||||||:|.||||||||||||||||||||||||||||||||||
  Rat   262 CEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMN 326

  Fly   405 IRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDEL-MTEESEEPLSD---DEA 465
            |||||||||||||||||||||||||||||||||||||:||||||:|: :.||.:..:|.   ...
  Rat   327 IRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDEEMSLVEEEDHYISSCPKGAT 391

  Fly   466 ALRKEVIRNKIRAIGKMARVFSVLREESESVLQLKGLTPTGALPLGALSGGKQSL---------- 520
            ::|||||||||||||||||||:|||||||:||.||||||||.||||.||||||::
  Rat   392 SVRKEVIRNKIRAIGKMARVFTVLREESENVLILKGLTPTGTLPLGVLSGGKQTIETAKLQAAEE 456

  Fly   521 KNAMQGFSPNHKITSFAEAKGLDAVNERMPPRRDAT---------PSP---AEEGQKSL 567
            :.|::||:..|:|.||.||:|||.:|||||||::|:         |.|   ::.|:|:|
  Rat   457 REAIRGFTIAHRIRSFEEARGLDRINERMPPRKEASYHHDAGKTHPHPSKRSDHGKKAL 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CanA-14F	NP_001245717.1	MPP_PP2B	115..419	CDD:277361	247/303 (82%)
CanA-14F	NP_001245717.1	PP2Ac	132..403	CDD:197547	221/270 (82%)
Ppp3cc	XP_008769035.1	MPP_PP2B	37..341	CDD:277361	247/303 (82%)
Ppp3cc	XP_008769035.1	PP2Ac	54..325	CDD:197547	221/270 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336038
Domainoid	1	1.000	92	1.000	Domainoid score	I7405
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D194337at33208
OrthoFinder	1	1.000	-	-		FOG0000983
OrthoInspector	1	1.000	-	-		mtm9101
orthoMCL	1	0.900	-	-		OOG6_100566
Panther	1	1.100	-	-	O	PTHR45673
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X576
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.720