Protein Alignment CG42594 and Kcnk10

DIOPT Version :9

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_075584.1
• Gene: Kcnk10 / 65272
• RGDID: 619732
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 487
• Identity: 101/487 - (20%)
• Similarity: 163/487 - (33%)
• Gaps: 187/487 - (38%)

  Fly   403 QQHQAVQGRHADNDTMAAAAAAVAAQGTLAGSASAGGLNPFGQPASSGEFVYGLDGMDATDLEAG 467
            |...|..|.|.......::.|.|.|:  :.| ||.|||    |.....:.|..:..:....|..|
  Rat    29 QPKSATNGHHPVPRLSISSRATVVAR--MEG-ASQGGL----QTVMKWKTVVAIFVVVVVYLVTG 86

  Fly   468 GMPQFALSPDTYDVRQRTIENIWDITVSLNILYKENWTKLAALEIAKF-QDQLIKRLNE-DVMLQ 530
            |:...||.......::.||                      |||.|:| :|.:.....| :.::|
  Rat    87 GLVFRALEQPFESSQKNTI----------------------ALEKAEFLRDHICVSPQELETLIQ 129

  Fly   531 --LSHDDVANAPSSSSSSSSSSSSSSSSTGASGVPGSNNPATEAVLLHTHYHHHRAGGVGGVAVG 593
              |..|:...:|..:||:|||
  Rat   130 HALDADNAGVSPVGNSSNSSS-------------------------------------------- 150

  Fly   594 GGPPHEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVA 658
                 .|:...||.::.||:|||||||:||.|..|:|..:.||.|||||....|:..|..|.
  Rat   151 -----HWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLG--- 207

  Fly   659 REVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPEK 723
             .:|.|::.                           |.::..||:|.
  Rat   208 -TIFGKSIA---------------------------RVEKVFRKKQV------------------ 226

  Fly   724 DAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYIVFGAAVLYR 788
                                              |...:.:::.||...:..|:::...|.:...
  Rat   227 ----------------------------------SQTKIRVISTILFILAGCIVFVTIPAVIFKY 257

  Fly   789 LEKWPILDGIYFCFMSLSTIGFGDMLPGLRRESNATTWFCSV---YIMSGMTLTAMCFNVI---- 846
            :|.|..|:.|||..::|:|:||||.:.|.....|...|:..:   :|:.|:...|...::|
  Rat   258 IEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWL 322

  Fly   847 -------HEEI----VH----RIRIVVEFKKT 863
                   .||:    .|    :..:..||::|
  Rat   323 RVLSKKTKEEVGEIKAHAAEWKANVTAEFRET 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	27/56 (48%)
		Ion_trans	<601..640	CDD:278921	19/38 (50%)
		Ion_trans_2	774..846	CDD:285168	20/74 (27%)
Kcnk10	NP_075584.1	Ion_trans_2	148..206	CDD:400301	29/106 (27%)
		Ion_trans_2	244..323	CDD:400301	21/78 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	412..444

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9664
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010