Protein Alignment CG42594 and KCNK10

DIOPT Version :9

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_612190.1
• Gene: KCNK10 / 54207
• HGNCID: 6273
• Length: 543
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 96/474 - (20%)
• Similarity: 160/474 - (33%)
• Gaps: 190/474 - (40%)

  Fly   417 TMAAAAAAVA-AQGTLAGSASAGGLNPFGQPASSGEFVYGLDGMDATDLEAGGMPQFALSPDTYD 480
            ::::.|..|| .:||     |.|||    |.....:.|..:..:....|..||:...||......
Human    49 SISSRATVVARMEGT-----SQGGL----QTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFES 104

  Fly   481 VRQRTIENIWDITVSLNILYKENWTKLAALEIAKF-QDQLIKRLNE-DVMLQ--LSHDDVANAPS 541
            .::.||                      |||.|:| :|.:.....| :.::|  |..|:...:|.
Human   105 SQKNTI----------------------ALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPI 147

  Fly   542 SSSSSSSSSSSSSSSTGASGVPGSNNPATEAVLLHTHYHHHRAGGVGGVAVGGGPPHEWNFAKAF 606
            .:||::||                                                 .|:...||
Human   148 GNSSNNSS-------------------------------------------------HWDLGSAF 163

  Fly   607 LYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVAREVFSKALCCCLC 671
            .::.||:|||||||:||.|..|:|..:.||.|||||....|:..|..|.    .:|.|::.
Human   164 FFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLG----TIFGKSIA---- 220

  Fly   672 SNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPEKDAGAGAPPPNAGG 736
                                   |.::..||:|.
Human   221 -----------------------RVEKVFRKKQV------------------------------- 231

  Fly   737 PVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYIVFGAAVLYRLEKWPILDGIYFC 801
                                 |...:.:::.||...:..|:::...|.:...:|.|..|:.|||.
Human   232 ---------------------SQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFV 275

  Fly   802 FMSLSTIGFGDMLPGLRRESNATTWFCSV---YIMSGMTLTAMCFNVI-----------HEEI-- 850
            .::|:|:||||.:.|.....|...|:..:   :|:.|:...|...::|           .||:
Human   276 VVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGE 340

  Fly   851 --VH----RIRIVVEFKKT 863
              .|    :..:..||::|
Human   341 IKAHAAEWKANVTAEFRET 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	27/56 (48%)
		Ion_trans	<601..640	CDD:278921	19/38 (50%)
		Ion_trans_2	774..846	CDD:285168	20/74 (27%)
KCNK10	NP_612190.1	Ion_trans_2	153..211	CDD:285168	28/106 (26%)
		Ion_trans_2	249..328	CDD:285168	21/78 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010