Protein Alignment CG42594 and KCNK18

DIOPT Version :9

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_862823.1
• Gene: KCNK18 / 338567
• HGNCID: 19439
• Length: 384
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 72/295 - (24%)
• Similarity: 120/295 - (40%)
• Gaps: 57/295 - (19%)

  Fly   600 WNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVAR----- 659
            |:|..:..:..||.:|:|||.:.|.|.||:.:.:.||.|||||..:.|:.||.|||.:..
Human   101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNR 165

  Fly   660 ----EVFSKALCCCLCSNCGYCCYDEKRMAEK------------------------ERRMRRKRQ 696
                ..|::.|....|....:....:.:.|::                        ...|....:
Human   166 FRKFPFFTRPLLSKWCPKSLFKKKPDPKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMELFER 230

  Fly   697 QEELRKQQAVMQEPYYVRDVFHATPEKDAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHG 761
            ...|.||. .:|.|....:..::.||...|.           .|...:.::|.:.....|
Human   231 SHALEKQN-TLQLPPQAMERSNSCPELVLGR-----------LSYSIISNLDEVGQQVER----- 278

  Fly   762 LSILAPILLCFSMMIIYIVFGAAVLYRLE-KWPILDGIYFCFMSLSTIGFGDMLPGLRRESNATT 825
            |.|..||:..  ::..||...||:|...| :....:..||||::|:||||||.:    .|.....
Human   279 LDIPLPIIAL--IVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV----LEHPNFF 337

  Fly   826 WFCSVYIMSGMTLTAMCFNVIHEEIVHRIRIVVEF 860
            .|.|:||:.||.:..:.|.::...::...:.|:.|
Human   338 LFFSIYIIVGMEIVFIAFKLVQNRLIDIYKNVMLF 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	24/55 (44%)
		Ion_trans	<601..640	CDD:278921	14/38 (37%)
		Ion_trans_2	774..846	CDD:285168	25/72 (35%)
KCNK18	NP_862823.1	Ion_trans_2	<100..155	CDD:285168	22/53 (42%)
		Interaction with calcineurin. /evidence=ECO:0000250	200..205		0/4 (0%)
		Interaction with YWHAH. /evidence=ECO:0000250	249..254		0/4 (0%)
		Ion_trans_2	288..364	CDD:285168	25/81 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155175
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41373
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950