DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42594 and twk-4

DIOPT Version :9

Sequence 1:	NP_001162668.2	Gene:	CG42594 / 8674091	FlyBaseID:	FBgn0260971	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_001343566.1	Gene:	twk-4 / 192079	WormBaseID:	WBGene00006659	Length:	418	Species:	Caenorhabditis elegans

Alignment Length:	364	Identity:	81/364 - (22%)
Similarity:	124/364 - (34%)	Gaps:	146/364 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   597 PHE---WNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVA 658
            |.|   |:...|..::.||||:|||||:.|.:|.|:|..:.||.||||||||.::
Worm   173 PQETSRWSMISAIFFTTTVLTSIGYGNLIPISTGGKIFCVGYAIFGIPLTLVTIA---------- 227

  Fly   659 REVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPEK 723
                                                    :|.|         :|.|:....|.:
Worm   228 ----------------------------------------DLAK---------FVADMLIMDPTE 243

  Fly   724 DAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYIVFGAAVLYR 788
            |...|..                                      ||....::.|:...|.|...
Worm   244 DPKTGRQ--------------------------------------LLVLVFLLGYMTISACVYTI 270

  Fly   789 LE-KWPILDGIYFCFMSLSTIGFGDMLPGLRRESNATTWFCS-VYIMSGMTLTAMCFNV------ 845
            || .|..||..|||.:||.|:||||:.|    ........|| |:|..|:.||.:..:|
Worm   271 LEPMWSFLDSFYFCLVSLLTVGFGDLHP----VGTVEYMLCSIVFIFIGLILTTLAVDVSGSVGI 331

  Fly   846 --IHE--------EIVHRIRIVVEFKKTSAANSGGGLIGGGSVS-GGAGGAGGSMMD--VAHEEG 897
              :|.        ::::.:|:    :|:.       .:..|:|| ..|....|..:|  ..|:..
Worm   332 AKMHSIGRGFDAMKMLNALRV----RKSE-------FVAKGAVSLSAAARVAGRRLDGQQPHQPR 385

  Fly   898 GQYYVPASX----HYEKRGHLYQRNPTEETLVTDTPTSL 932
            ...|||..     :.::..::..|.      .|.|.||:
Worm   386 WFAYVPKDALTIPYIDESANVSSRT------TTTTHTSI 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	26/59 (44%)
		Ion_trans	<601..640	CDD:278921	17/38 (45%)
		Ion_trans_2	774..846	CDD:285168	27/81 (33%)
twk-4	NP_001343566.1	Ion_trans_2	<178..235	CDD:311712	28/115 (24%)
twk-4	NP_001343566.1	Ion_trans_2	255..329	CDD:311712	27/77 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920