Protein Alignment CG42594 and twk-13

DIOPT Version :9

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_001122984.1
• Gene: twk-13 / 192077
• WormBaseID: WBGene00006668
• Length: 625
• Species: Caenorhabditis elegans
• Alignment Length: 657
• Identity: 138/657 - (21%)
• Similarity: 217/657 - (33%)
• Gaps: 208/657 - (31%)

  Fly   350 IENEDSALLHQQHTLASTKRNLAGLGIGAAGIGSSIYQQQQQQQQQRTPHQQQQQHQAVQGRHAD 414
            :..:.|....|:|...|:    .|:.:|......|:|..||
 Worm    18 VSYQPSTSSFQRHHRPSS----PGISLGPPSSPPSLYNLQQ------------------------ 54

  Fly   415 NDTMAAAAAAVAAQGTLAGSASAGGLNPFGQPASSGEFVYGLDGMDATDLEAGGMPQFALSPDTY 479
                .|:|..|..|.......||..||.:                  .|.|.|.:.......|
 Worm    55 ----IASATGVDQQNNDVEELSAERLNLY------------------LDKEEGEIENLEEEID-- 95

  Fly   480 DVRQRTIENIWDITVSLNILYKENWTKLA-------ALEIA--------------KFQDQL---- 519
                .|.|..|       .|..:.|.:||       .|.|.              .::.||
 Worm    96 ----ETTEKKW-------WLRTKRWFRLALPHFGLVLLSIGYTLIGALCFHHYEKPYEQQLRNET 149

  Fly   520 ---IKRLNEDVMLQLSHDDVANAPSSSSSSSSSSSSSSSSTGASGVPGSNNPATEAVLLHTHYHH 581
               |..|...||.||..          .|::.::.|:...|...|:        :.::....:.:
 Worm   150 SRRIGELKNRVMDQLWR----------MSNNGTAYSTWRQTANDGM--------DELIRDVFWDY 196

  Fly   582 HRAGGVGGVAVGGGPPHEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVY 646
            .|........:.|..|.:|:|..:..:|.|.:||||||::.|||..||:..:.||..||||.||.
 Worm   197 TRNYMTPDDVIYGDGPIKWSFMSSIFFSWTAITTIGYGHIVPRTDEGRVAIIFYALLGIPLILVT 261

  Fly   647 LSSTGSILARVA-------REVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQ------E 698
            ::..|..||...       ..|.|.....||......||:           :|..|:.      |
 Worm   262 IADIGRFLATYIIKLHHGYMAVMSFVTNSCLKCIKWACCW-----------IRLPRRHIPMPTLE 315

  Fly   699 ELRKQQAVMQEPYYVRDVFHATPEKDAGAGAPPPNAGGPVG--------SVGGLGDIDSLS---- 751
            .|::.|.:...            ..:....|...:|||..|        :|...|..|::|
 Worm   316 LLQRTQKLYPN------------NNNPTVAATAASAGGGTGRRKKQQRDNVSDAGTFDNISEIND 368

  Fly   752 -----ASESRG----------SMHGLSILAPILLCFSMMIIYIVFGAAVLYRLEKWPILDGIYFC 801
                 .:|:.|          |.|...:  .:|....:|:.|:..||.::...|:|...:..|||
 Worm   369 GSEGGENENEGEEEEQIQFDPSNHEKRV--SVLFILLIMLGYVAGGAYIVRWWEEWTFFEAFYFC 431

  Fly   802 FMSLSTIGFGDMLPGLRRESNATTWFCS--VYIMSGMTLTAMCFNVIHEEIVHRIRIVVEFKKTS 864
            |::::||||||::|.      ...|..:  .||:.|:.:|.||.:::..|.:..|..........
 Worm   432 FVTVTTIGFGDIVPA------NVDWLPATLAYIVFGLIITTMCIDLVGSEYIRDIHFYGRSLGRQ 490

  Fly   865 AANSGGGLIGGGSVSG---------GAGGAGGSMMDVAHEE-----------------GGQYYVP 903
            ....||.::..|.|.|         |......:.:....||                 ||:.|||
 Worm   491 FMTIGGKVVHLGEVFGYVAFLQKNYGLTAEQLTKLSQLPEEYLLDCLINGRQPDLNWIGGRPYVP 555

  Fly   904 ASXHYEK 910
            .. :|.|
 Worm   556 PDIYYFK 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	25/56 (45%)
		Ion_trans	<601..640	CDD:278921	16/38 (42%)
		Ion_trans_2	774..846	CDD:285168	24/73 (33%)
twk-13	NP_001122984.1	Ion_trans_2	<214..269	CDD:285168	24/54 (44%)
		Ion_trans	<398..464	CDD:278921	22/71 (31%)
		Ion_trans_2	403..478	CDD:285168	25/80 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020