DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42594 and twk-32

DIOPT Version :9

Sequence 1:	NP_001162668.2	Gene:	CG42594 / 8674091	FlyBaseID:	FBgn0260971	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_506416.2	Gene:	twk-32 / 192075	WormBaseID:	WBGene00006684	Length:	614	Species:	Caenorhabditis elegans

Alignment Length:	270	Identity:	69/270 - (25%)
Similarity:	111/270 - (41%)	Gaps:	66/270 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   598 HEW-----------NFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTG 651
            |.|           ||.....::.|.||:||||..||.:.:||:..|.|.||||||.|:.::.
Worm   111 HRWQEAAFNANPLTNFTSNLFFAATTLTSIGYGIDAPESLIGRVFCLVYLFFGIPLYLITIAD-- 173

  Fly   652 SILARVAREVFSKALCCCLCSNCGYCCYDE--KRMAEKERRMRRKRQQEELRKQQAVMQEPYYVR 714
              :|:...|:.::.             |.|  |.....:||.:|.:.....|:...|
Worm   174 --MAKFCTELMNRT-------------YTEIIKYKYRVKRRYKRWKSGRIRRESMKV-------- 215

  Fly   715 DVFHATPEKDAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYI 779
                                 |.|...||..::.....:...   |...:..|.||...::::||
Worm   216 ---------------------GQVIIAGGEDEVAEFLWTHLE---HAQFVEVPFLLVIGILLLYI 256

  Fly   780 VFGAAVLYRLEKWPILDGIYFCFMSLSTIGFGDMLPGLRRESNATTWFCSVYIMSGMTLTAMCFN 844
            ...:.::..:|.|.::||.||..||:.||||||::|  |.|..|..  ....|::|:.||..|.:
Worm   257 GLSSWIISWVENWNMMDGFYFVMMSVLTIGFGDLVP--RNEIFAVP--ILFIILAGLVLTTTCID 317

  Fly   845 VIHEEIVHRI 854
            |:....:.|:
Worm   318 VVGAYYIDRL 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	23/67 (34%)
		Ion_trans	<601..640	CDD:278921	17/38 (45%)
		Ion_trans_2	774..846	CDD:285168	25/71 (35%)
twk-32	NP_506416.2	Ion_trans_2	<125..180	CDD:285168	23/58 (40%)
		Ion_trans_2	251..325	CDD:285168	26/77 (34%)
		FN3	392..485	CDD:238020
		FN3	491..580	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910