Protein Alignment CG42594 and twk-7

DIOPT Version :9

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_498903.3
• Gene: twk-7 / 192073
• WormBaseID: WBGene00006662
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 669
• Identity: 120/669 - (17%)
• Similarity: 212/669 - (31%)
• Gaps: 277/669 - (41%)

  Fly   308 SKEKKKSRKATSQTVWSAL-LTNLGICMLLLAYTLLGSFIFLTIENEDSALLHQQHTLASTKRNL 371
            ||::.:..:.|....::.| |.::.:.:|...||::|:.||.::|        |.|
 Worm   143 SKDEDEEEEETGIRKFAKLVLPHVALVLLTCTYTVIGALIFYSVE--------QPH--------- 190

  Fly   372 AGLGIGAAGIGSSIYQQQQQQQQQRTPHQQQQQHQAVQGRHADNDTMAAAAAAVAAQGTLAGSAS 436
                           :|..::||.:..:.:|
 Worm   191 ---------------EQMMKEQQLKLIYTRQ---------------------------------- 206

  Fly   437 AGGLNPFGQPASSGEFVYGLDGMDATDLEAGGMPQFALSPDTYDVRQRTIENIWDITVSLNILYK 501
                         .|||     .|...|.||                             |...:
 Worm   207 -------------NEFV-----DDLIRLAAG-----------------------------NETKR 224

  Fly   502 ENWTKLAALEIAKFQDQLIKRLNEDVMLQLSHDDVANAPSSSSSSSSSSSSSSSSTGASGVPGSN 566
            ..|..||...:....|||.....:   ..|:.::|                            ..
 Worm   225 YEWESLAERHMHNMSDQLFVAFEK---YFLTSNEV----------------------------KK 258

  Fly   567 NPATEAVLLHTHYHHHRAGGVGGVAVGGGPPHEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIV 631
            |.|||.                           |.|:.:..:::||:|||||||..|.|.:|||.
 Worm   259 NAATET---------------------------WTFSSSIFFAVTVVTTIGYGNPVPVTNIGRIW 296

  Fly   632 TLAYAFFGIPLTLVYLSSTGSILARVAREVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQ 696
            .:.::..|||||||.::..|..|:.....::...|                    |.:.:...|.
 Worm   297 CILFSLLGIPLTLVTIADLGKFLSEHLVWLYGNYL--------------------KLKYLILSRH 341

  Fly   697 QEELRKQQAVMQEPYYVRDVFHATPEKDAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHG 761
            ::|.|:         :|.:..|                                    |.|..|.
 Worm   342 RKERRE---------HVCEHCH------------------------------------SHGMGHD 361

  Fly   762 LSI---LAPILLCFSMMIIYIVFGAAVLYRLEKWPILDGIYFCFMSLSTIGFGDMLPGLRRESNA 823
            ::|   ..|..|..:::|:|..||..::.:||.|......|:.|::::|:||||::|  ||:  .
 Worm   362 MNIEEKRIPAFLVLAILIVYTAFGGVLMSKLEPWSFFTSFYWSFITMTTVGFGDLMP--RRD--G 422

  Fly   824 TTWFCSVYIMSGMTLTAMCFNVIHEEIVHRIRIVVEFKKTSAANSGGGLIGGGSVSGGAGGAGGS 888
            ..:...:||:.|:.:|.||.:::..:.:.:|...  .:|...|.|...::||
 Worm   423 YMYIILLYIILGLAITTMCIDLVGVQYIRKIHYF--GRKIQDARSALAVVGG------------- 472

  Fly   889 MMDVAHEEGGQYYVPASXHYEKRGHLYQRNPTEETLVTDTPTSLVLKDYVNHELVPILTMDPNGA 953
                       ..|..| .|........||.:.|..:.:..       ||:..::|.:..|....
 Worm   473 -----------KVVLVSELYANLMQKRARNMSREAFIVENL-------YVSKHIIPFIPTDIRCI 519

  Fly   954 RLAPTPAPAYTPANTSTGM 972
            |.....|.|.|.:.:|:.:
 Worm   520 RYIDQTADAATISTSSSAI 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	25/56 (45%)
		Ion_trans	<601..640	CDD:278921	15/38 (39%)
		Ion_trans_2	774..846	CDD:285168	23/71 (32%)
twk-7	NP_498903.3	Ion_trans_2	<263..321	CDD:285168	26/84 (31%)
		Ion_trans	<371..>418	CDD:278921	15/46 (33%)
		Ion_trans_2	377..>422	CDD:285168	17/48 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020