Protein Alignment CG42594 and twk-1

DIOPT Version :10

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_001293466.1
• Gene: twk-1 / 192072
• WormBaseID: WBGene00006656
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 257
• Identity: 50/257 - (19%)
• Similarity: 92/257 - (35%)
• Gaps: 98/257 - (38%)

  Fly   598 HEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVAREVF 662
            :|.:|....|:.:|.::||||||:||....|:::.:.|...||||..:.: :|.|:|.
 Worm    98 NEASFLDRALFCITTISTIGYGNIAPFDDRGKVICILYCVAGIPLFFMTV-ATNSVLV------- 154

  Fly   663 SKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPEKDAGA 727
                 ..:|:                                 ::...|..::|
 Worm   155 -----VDICN---------------------------------IVHRSYSSQNV----------- 170

  Fly   728 GAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYIVFGAAVLYRLEKW 792
                                      |:.|.....|.:.....||...:|:.::       :::.
 Worm   171 --------------------------ENSGFRWYTSAILLAAHCFIGALIFSLW-------IDQL 202

  Fly   793 PILDGIYFCFMSLSTIGFGDMLP---GLRRESNATTWFCSVYIMSGMTLTAMCFNVIHEEIV 851
            ..||..||.|:|::|||:||..|   ||.:....|     ||:.:|:....:.|..:.:.|:
 Worm   203 DFLDAFYFSFISITTIGYGDYSPTPEGLFQYIIVT-----VYLCTGVATMLLFFASLQKGIM 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:462301	21/56 (38%)
		Ion_trans_2	774..846	CDD:462301	20/74 (27%)
twk-1	NP_001293466.1	Ion_trans_2	76..149	CDD:462301	18/51 (35%)
		Ion_trans_2	182..256	CDD:462301	22/85 (26%)