Protein Alignment CG42594 and twk-2

DIOPT Version :9

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_001350984.1
• Gene: twk-2 / 188452
• WormBaseID: WBGene00006657
• Length: 1519
• Species: Caenorhabditis elegans
• Alignment Length: 460
• Identity: 100/460 - (21%)
• Similarity: 176/460 - (38%)
• Gaps: 123/460 - (26%)

  Fly   497 NILYKEN------WTKLAALEIAKFQDQLIKRLNEDVMLQLSHDDVANAPSSSSSSSSSSSSSSS 555
            |::||.|      |.:....|:..:.::|.|...|.   .:.:.||    .:......||...:.
 Worm    80 NLIYKINNNEKEVWKEDIEKELMLYSEKLYKAFKEQ---YVRYSDV----RTIGFEGRSSYEEAD 137

  Fly   556 STGASGVPGSNNPATEAVLLHTHYHHHRAGGVGGVAVGGGPPHEWNFAKAFLYSLTVLTTIGYGN 620
            .||.           ::.....|.|.::.|..|...:       |..:.|..::.|.:.||||||
 Worm   138 ETGG-----------DSERKRRHRHGNKRGDRGSEKM-------WTTSSALFFAATTMATIGYGN 184

  Fly   621 VAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVAREVFSKALCCCLCSNCGYCCYDEKR-- 683
            :.|.|.|||:..:.:|.||.|:.::.:...|..|                 |.|....|...|
 Worm   185 IVPVTPLGRLACVLFALFGAPIAIITIGDLGKFL-----------------SECTIWLYKHMRKG 232

  Fly   684 MAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPEKDAGAGAPPPNAGGPVGSVGGLGDID 748
            .|..:...:|.|..|:....           |:..|:..:|:              |:..: |:|
 Worm   233 SARLDSAWKRFRGLEDSISD-----------DLESASKNQDS--------------SILDM-DMD 271

  Fly   749 SLSASESRGSMHGLSILAPILLCFSMMIIYIVFGAAVLYRLEKWPILDGIYFCFMSLSTIGFGDM 813
            .:..||           .|:|:.|:::::||.||..:...||.|..:|..|:.|:||:||||||:
 Worm   272 EIDKSE-----------VPVLMVFTIILLYIAFGGILFSILEDWSYMDAFYYSFISLTTIGFGDI 325

  Fly   814 LPGLRRESNATTWFCSVYIMSGMTLTAMCFNVIHEEIVHRIRI---------VVEFKKTSAANSG 869
            :|    |::.......:|:..|:::|.||.::...:.:.:|..         ::::.|.......
 Worm   326 VP----ENHDYIAIMLIYLGVGLSVTTMCIDLAGIQYIQKIHYFGRKFQGTDLLQYLKKKRMLER 386

  Fly   870 GGLIGGGSVSGGAGGAGGSMMDVAHEEGGQYYVPASXHYEKRGHLYQRNPTEETLVTDTPTSLVL 934
            ...:|.|                  ||..:.||.|. .:|:.....|:...||     .|.|:..
 Worm   387 RLAMGQG------------------EEILRKYVHAVEKFEREQEQLQQKMEEE-----DPPSIES 428

  Fly   935 KDYVN 939
            |.:.|
 Worm   429 KGFDN 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	20/56 (36%)
		Ion_trans	<601..640	CDD:278921	15/38 (39%)
		Ion_trans_2	774..846	CDD:285168	25/71 (35%)
twk-2	NP_001350984.1	Ion_trans_2	<164..220	CDD:311712	20/72 (28%)
		Ion_trans_2	285..360	CDD:311712	25/78 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020