Protein Alignment CG42594 and unc-58

DIOPT Version :9

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_001360793.1
• Gene: unc-58 / 181224
• WormBaseID: WBGene00006792
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 694
• Identity: 138/694 - (19%)
• Similarity: 228/694 - (32%)
• Gaps: 253/694 - (36%)

  Fly   211 MATPPSRKEPLTPAHP---QAASIQAQAQVQHQLQQQHQQQQQQQQQQHQQQQQQQQQRQRKRQG 272
            |..|...|:.....||   |:::.|.||.:...|..||..|....:.|               .|
 Worm     1 MVFPQVTKDLQKEGHPRRLQSSAGQHQALIMQPLVVQHYAQNVHTEVQ---------------LG 50

  Fly   273 WCSCFSSTPGGGHAGGGVGGGVAAGETGKTPPGYGSKEKKKSRKATSQTVWSALLTNLGICMLLL 337
            .....|   |||..|||.|||.......:|.|     :..:.|
 Worm    51 LAPPLS---GGGSTGGGSGGGFFGSGLFRTRP-----QSNRPR---------------------- 85

  Fly   338 AYTLLGSFIFLTIENEDSALLHQQHTLAS-TKRNLAGLGIGAAGIGSSIYQQQQQQQQQRTPHQQ 401
            ||::|.  :..:|..|:.|     :.||| ||::                  ..:..::..|..|
 Worm    86 AYSMLP--LTSSISQEEKA-----NILASNTKKH------------------SNRSHKRYYPLSQ 125

  Fly   402 QQQHQAVQGRHADNDTMAAAAAAVAAQGTLAGSASAGGLNPFGQPASSGEFVYGLDGM--DATDL 464
            :...:.:...:.|:.|.....|.:.:|..|.             .|..|..|. .|.:  |..|.
 Worm   126 EDTLELLLLLNQDHVTARWEGANINSQSALL-------------DADDGATVI-TDTIKDDQDDK 176

  Fly   465 EAGGMPQFALSPDTYDVRQRTIENIWDIT-------VSLNILYKENWTKLAALEIAKFQDQLIKR 522
            |....|            |:|::.|..:|       |.:..|....|    .|.:.:.:.:|:.|
 Worm   177 EPKSCP------------QQTVKYIKILTPHVILVSVLIGYLCLGAW----ILMLLETRTELLAR 225

  Fly   523 LNEDVMLQLSHDDVANAPSSSSSSSSSSSSSSSSTGASGVPGSNNPAT---------EAV----- 573
            ..:.|.|       .|. .|:.::.|....:::..|.|.:......||         |.|
 Worm   226 SKKLVRL-------TNL-MSNFTAESWKMLNNAQHGVSNMDEGEWAATFREWMVRVSETVDDRRP 282

  Fly   574 ----------LLHTHYHHHRAGGVGGVAVGGGPPHEWNFAKAFLYSLTVLTTIGYGNVAPRTTLG 628
                      |.:.|                   ::|.|..|.||.||||||.|||.|:..|.:|
 Worm   283 IRRELNRPDDLSNMH-------------------NKWTFPTAILYVLTVLTTCGYGEVSVDTDVG 328

  Fly   629 RIVTLAYAFFGIPLTLVYLSSTGSILA-----------RVAREVFSKALCCCLCSNCGYCCYDEK 682
            ::.::|:|..||||..:..:..|..|:           |..|:|                    |
 Worm   329 KVFSVAFALVGIPLMFITAADIGKFLSETLLQFVSFWNRSVRKV--------------------K 373

  Fly   683 RMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPEKDAGAGAPPPNAGGPVGSVGGLGDI 747
            :...:.|..|||..|                                   :.|||..::    ||
 Worm   374 QWMSRIRHGRRKSLQ-----------------------------------STGGPNDTL----DI 399

  Fly   748 DSLSASESR------GSMHGLSILAPILLCFSMMIIYIVFGAAVLYRLEK-WPILDGIYFCFMSL 805
            ..:..:|.:      .:.....:..||....|.:.||...|:|:....|: |..:...:|.|..:
 Worm   400 LGVDGTEEKLWFPIVPNGERTKLWFPIGAYVSCICIYCSIGSAMFITWERTWSFIHAFHFGFNLI 464

  Fly   806 STIGFGDMLPGLRRESNATTW-FCSV---YIMSGMTLTAMCFNV 845
            .|:|.||::        .|.: |.|:   :::.|:::..||.::
 Worm   465 VTVGLGDIV--------VTDYIFLSLIVAFVIVGLSVVTMCVDL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	25/67 (37%)
		Ion_trans	<601..640	CDD:278921	18/38 (47%)
		Ion_trans_2	774..846	CDD:285168	18/77 (23%)
unc-58	NP_001360793.1	Ion_trans_2	<299..355	CDD:369572	24/55 (44%)
		Ion_trans_2	435..498	CDD:369572	17/70 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010