Protein Alignment CG42594 and twk-33

DIOPT Version :9

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_001309463.1
• Gene: twk-33 / 180161
• WormBaseID: WBGene00006685
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 791
• Identity: 134/791 - (16%)
• Similarity: 234/791 - (29%)
• Gaps: 309/791 - (39%)

  Fly   241 LQQQHQQQQQQ--QQQQHQQQQQQQQQRQRKRQGWCSCFSSTPGGGHAGGGVGGGVAAGETGKTP 303
            |::.|:::|..  ::.:...::....:...||:                    ..:.:.||.:..
 Worm    22 LEEIHEEEQDSIPEEDETNLEKPSHSENDFKRK--------------------NAIRSEETPEIS 66

  Fly   304 P-------GYGSKEKKKSRKATSQTVWSALLTNLGICMLLLAYTLLGSFIFLTIENEDSALLHQQ 361
            |       ...|.:::::.|..::::                          ::.|.|   |.::
 Worm    67 PEIQRIEDPLASSDEEENEKPFARSI--------------------------SVSNAD---LEER 102

  Fly   362 HTLASTKRNLAGLGIGAAGIGSSIYQQQQQQQQQRTPHQ---------QQQQHQAVQGRHADNDT 417
            |.|                  .||.:..:.||.:.|.|.         |......|:..:..|:.
 Worm   103 HRL------------------DSIPENDRSQQSRYTRHSSIDKGILKPQNNSEDVVEKYYERNNY 149

  Fly   418 MAAAAAAVAAQGTLAG------SASAGGLNPFGQPASSGE-FVYGLDGMDATDLEAGGMPQFALS 475
            .............|.|      |......:.|..|.:.|| .|..|...|.:      |..||..
 Worm   150 TVTGRDRPDFYNKLPGRLQHRLSVHTDAASRFSSPGAMGEPVVPTLRRFDKS------MYWFAFH 208

  Fly   476 PDTYDVRQRTIENIWDITVSLNILYK-----ENWTKLAALEIAKFQD------QLIKRLNEDVML 529
            ......|..::       |.|.:||.     ..||..:..|.||..|      .|:.||.|::.
 Worm   209 RKQIGFRHFSV-------VILVLLYTLLGAVMFWTVESRHEKAKTLDHVNNLEHLLDRLAENIT- 265

  Fly   530 QLSHDDVANAPSSSSSSSSSSSSSSSSTGASGVPGSNNPATEAVLLHTHYHHHRAGGVGGVAVGG 594
                :.|.|..::::..........:......:.|....:|        |:...|
 Worm   266 ----ESVNNINTTTTEEEMKVYIREAYIELMKLEGQYKGST--------YYKLEA---------- 308

  Fly   595 GPPHEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGSILARVAR 659
            ....:|.|..||.:|:.|.||.|||::||.:|||:::...|.|..:|:|||.|...|........
 Worm   309 DDNWKWTFESAFFFSMNVYTTTGYGSIAPESTLGQVLVCVYGFIFVPVTLVVLRDLGQFFLVHLT 373

  Fly   660 EVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVFHATPEKD 724
            ::::..:                   :|.|.:...:..:|
 Worm   374 KLYAHGI-------------------QKFRELNGNKHVDE------------------------- 394

  Fly   725 AGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYIVFGAAVLYRL 789
                                .:|.||                ||..|..::..|:  ||..:: :
 Worm   395 --------------------DEIISL----------------PIKACLLLLASYL--GACTIF-I 420

  Fly   790 EKWPILDG------------IYFCFMSLSTIGFGDMLPGLRRESNAT-TWFCSVYIMSGMTLTAM 841
            ..:..|.|            .||.|:||||||.||::|     :||| ....|:....||.:|.:
 Worm   421 YFYDELSGPEPGTGMDMFLCFYFSFISLSTIGLGDIMP-----NNATFAPIISIIFFFGMAVTKV 480

  Fly   842 ---------------CFNVIHEEI---------------------VHR----------------- 853
                           .|.::..::                     |.|
 Worm   481 VNRNTFIAVENGIFGAFTLVENKLDAIVTRSSASVKPEDRPSTPKVQRALSVDAGSEVQDETPNE 545

  Fly   854 ------IRIVVEFKKTSAANSGGGLIGGGSVSGGAGGAGGSMMDVAHEEGGQYYVPASXHYEKRG 912
                  :|.:..|.|::|...|||.   |.|....|       |:.|.:........| ...:..
 Worm   546 ILNNLTVRSIATFMKSNADIYGGGF---GRVQLRRG-------DLIHSDSQNQMTVNSMSQLRHR 600

  Fly   913 HLYQRNPTEET 923
            ...|..|.:.|
 Worm   601 TASQSQPNQAT 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	24/56 (43%)
		Ion_trans	<601..640	CDD:278921	17/38 (45%)
		Ion_trans_2	774..846	CDD:285168	25/99 (25%)
twk-33	NP_001309463.1	Hid1	<9..141	CDD:301632	22/185 (12%)
		Ion_trans_2	300..368	CDD:285168	27/85 (32%)
		Ion_trans	<404..498	CDD:278921	25/101 (25%)
		Ion_trans_2	407..491	CDD:285168	24/91 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163810
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940