Protein Alignment CG42594 and Kcnk5

DIOPT Version :10

• Sequence 1: NP_001162668.2
• Gene: CG42594 / 8674091
• FlyBaseID: FBgn0260971
• Length: 1039
• Species: Drosophila melanogaster
• Sequence 2: NP_067517.1
• Gene: Kcnk5 / 16529
• MGIID: 1336175
• Length: 502
• Species: Mus musculus
• Alignment Length: 542
• Identity: 106/542 - (19%)
• Similarity: 164/542 - (30%)
• Gaps: 243/542 - (44%)

  Fly   589 GVAVGGGPP-HEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSSTGS 652
            |||:.|... :.||:..|.:::.||:||||||||||:|..||:..:.|..||:||.|.::|:.|.
Mouse    71 GVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTWISALGK 135

  Fly   653 ILARVAREVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVRDVF 717
            .....|                       ||:.:     ...|:...|||.|......:.|..|
Mouse   136 FFGGRA-----------------------KRLGQ-----FLTRRGVSLRKAQITCTAIFIVWGV- 171

  Fly   718 HATPEKDAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYIVFG 782
                                                                      ::::|..
Mouse   172 ----------------------------------------------------------LVHLVIP 178

  Fly   783 AAVLYRLEKWPILDGIYFCFMSLSTIGFGDMLPGLRRESN---ATTWFCSVYIMSGMTLTAMCFN 844
            ..|....|:|..::|:|:.|:::|||||||.:.|:...:|   ...:|..::|..|:...::..|
Mouse   179 PFVFMVTEEWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVN 243

  Fly   845 -------VIHEEIVHRIR------------------------------------------IVVEF 860
                   .:|:.|..|.|                                          ::.:.
Mouse   244 WKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQMAGSTASKDVNIFSFLSKKEETYNDLIKQI 308

  Fly   861 KKTSAANSGGG--------------------------------------------LIGGGSVSGG 881
            .|.:...||||                                            |...|.||..
Mouse   309 GKKAMKTSGGGERVPGPGHGLGPQGDRLPTIPASLAPLVVYSKNRVPSLEEVSQTLKNKGHVSRP 373

  Fly   882 AGGAGG---------------SMMDVAHEEGGQY----YVP-----ASXHYEKRGHLYQRNPTEE 922
            .|...|               :.:|...|||..:    |.|     |: .:|          .||
Mouse   374 LGEEAGAQAPKDSYQTSEVFINQLDRISEEGEPWEALDYHPLIFQNANITFE----------NEE 428

  Fly   923 TLVTDTPTSLVLKDYVNHELVPILTMDPNGARLAPTPAP-AYTPANTSTGMPGSGEVTTPGNSCI 986
            |.::|..||   |..|...|.         ::..|...| |..|.:::...|.|.|.|.....
Mouse   429 TGLSDEETS---KSSVEDNLT---------SKEQPEQGPMAEAPLSSTGEFPSSDESTFTSTE-- 479

  Fly   987 AHGSDPGLGYSSLSSPLLDVMN 1008
                      |.||.|...:||
Mouse   480 ----------SELSVPYEQLMN 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:462301	26/56 (46%)
		Ion_trans_2	774..846	CDD:462301	20/81 (25%)
Kcnk5	NP_067517.1	Ion_trans_2	<83..137	CDD:462301	26/53 (49%)
		Ion_trans_2	171..243	CDD:462301	20/130 (15%)