DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FDY and Habp4

DIOPT Version :9

Sequence 1:	NP_001303579.2	Gene:	FDY / 8674077	FlyBaseID:	FBgn0265047	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001073409.1	Gene:	Habp4 / 361196	RGDID:	1306486	Length:	411	Species:	Rattus norvegicus

Alignment Length:	347	Identity:	91/347 - (26%)
Similarity:	138/347 - (39%)	Gaps:	99/347 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SGLEQPQIAAVVAAPKKPEPAKAPKVPK---------------------SKSEKENKPVVAGRKA 63
            |..:||.      :|..|:|....:.|:                     .:|.:|.:|....|:|
  Rat   101 SSAQQPD------SPGGPQPPGQKRTPRRGEQQGWNDNRGTDVVLDRAERRSYREYRPYDTERQA 159

  Fly    64 NTPVAK-----------NASPVKGGKGPAGGDVGRPKNPTANGANNQGRFNNNQRYGNKESIGEF 117
            .:...|           ...|::|..||.|            |..|:||             |..
  Rat   160 ESTAEKFTDEKPVDRFDRDRPLRGRGGPRG------------GLRNRGR-------------GGP 199

  Fly   118 GNELPQRQFNNRDNRGPPRVRSGEKFGKREFDRQSGSDKTGVKSIDKREGVGAHNWGSPK--QDI 180
            ||    |.|::.|.|           |||:|:|...|||.. :..|...|.|...|||.|  .|.
  Rat   200 GN----RAFDSFDQR-----------GKRDFERYGSSDKAN-RMEDSMGGCGVRTWGSGKDTSDT 248

  Fly   181 EDLKTTGETSPQAEKKDSANEQSAD--PAVAAEED-ESKQMTLDEWKALRDQ-RAKPNYNLRKAG 241
            |......|||...|.:...:|:||.  |.:..||: :.::|||||||.|::| |.||.:|:||
  Rat   249 EPPAPMEETSMMEECQGVLDEESASKVPELEVEEENQVQEMTLDEWKNLQEQTRPKPEFNIRK-- 311

  Fly   242 EGAADNAEWKKMIVLSKKKESNS--EDELEYDPSLYPQRVGRLQRIVDIQFNFNDGRKGGFRKGT 304
               .::....|.:|:.|.:..:.  :|:.|.:..::.:....:...::|.|. |..|.|...:|:
  Rat   312 ---PESTVPSKAVVIHKSRYRDDIVKDDYEDESHVFRKAANDITSQLEINFG-NLPRPGRGARGS 372

  Fly   305 RRGAGPCEGGFR---NDGPRGE 323
            .||.   .|..|   |.|||.|
  Rat   373 TRGG---RGRIRRTENYGPRAE 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FDY	NP_001303579.2	HABP4_PAI-RBP1	144..242	CDD:335891	42/103 (41%)
FDY	NP_001303579.2	PRK11634	<308..368	CDD:236941	7/19 (37%)
Habp4	NP_001073409.1	IHABP4_N	16..162	CDD:406560	12/66 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..317		71/267 (27%)
		HABP4_PAI-RBP1	211..314	CDD:398441	42/108 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	358..411		14/38 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I4446
OMA	1	1.010	-	-		QHG48663
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002116
OrthoInspector	1	1.000	-	-		mtm9023
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12299
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1570
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.070