Protein Alignment FDY and SERBP1

DIOPT Version :9

• Sequence 1: NP_001303579.2
• Gene: FDY / 8674077
• FlyBaseID: FBgn0265047
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001018077.1
• Gene: SERBP1 / 26135
• HGNCID: 17860
• Length: 408
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 128/471 - (27%)
• Similarity: 181/471 - (38%)
• Gaps: 154/471 - (32%)

  Fly     7 NRYELLFMDDDD----------------SSGLEQPQIAAVVAAPKKPEPAKAPKVPKSKSEKENK 55
            ||::.||.|:.|                ..|:..|...:...|..:.....|.|..:.:|:|:.|
Human    15 NRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRK 79

  Fly    56 -PV-----VAGRKANT--PVAKNASPVKGGKGPAGGDVGRPKNPTANGANN------QGRFNNNQ 106
             |:     |..:|..|  |||.....::        .|||..:....|...      :.|....:
Human    80 NPLPPSVGVVDKKEETQPPVALKKEGIR--------RVGRRPDQQLQGEGKIIDRRPERRPPRER 136

  Fly   107 RY----GNKESIGEFGNELP--QRQFNNRDNRGPPR------VRSGEKF---GKREFDRQSGSDK 156
            |:    ..|...|||..:.|  .|....|...|..|      :..|:.|   |||||||.||||:
Human   137 RFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDR 201

  Fly   157 ------TGVKSIDKREGVGAHNWG--------SPK----------QDIEDLKTTGETSPQAEK-- 195
                  :|:|..|||.|.|:||||        |||          .|::....|.|| |:.|:
Human   202 SSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQKQISYNYSDLDQSNVTEET-PEGEEHH 265

  Fly   196 --KDSANEQSADPAVAAEEDESKQMTLDEWKALRDQ-RAKPNYNLRKAGEGAADNAEWKKMIVL- 256
              .|:.|:::....|  :|:..|:||||||||:::: |||..:|:||..|||  :.:|||..||
Human   266 PVADTENKENEVEEV--KEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA--DGQWKKGFVLH 326

  Fly   257 -SKKKESNSEDELEYDPSLYPQRVGRLQRIVDIQFNFNDGRKGGFRKGTRRGAGPCEGGFRNDGP 320
             ||.:|:::||.                 ::|..          |||.........|..|.:.|.
Human   327 KSKSEEAHAEDS-----------------VMDHH----------FRKPANDITSQLEINFGDLGR 364

  Fly   321 RGEGGYRNDGPRGEGGYRNEGPRGEGYRNDGPREQGFRGPRFNNAPSNGYENRQDNNRFGEKRRS 385
            .|.||....|.||.||..|.|.|.:                                     :.|
Human   365 PGRGGRGGRGGRGRGGRPNRGSRTD-------------------------------------KSS 392

  Fly   386 AEKPLKVDDEAQFPTL 401
            |..| .|||...||.|
Human   393 ASAP-DVDDPEAFPAL 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FDY	NP_001303579.2	HABP4_PAI-RBP1	144..242	CDD:335891	50/126 (40%)
		PRK11634	<308..368	CDD:236941	14/59 (24%)
SERBP1	NP_001018077.1	IHABP4_N	5..152	CDD:406560	30/144 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..292		71/269 (26%)
		HABP4_PAI-RBP1	189..313	CDD:398441	50/126 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..408		32/145 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	79	1.000	Domainoid score	I8662
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I4546
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48663
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002116
OrthoInspector	1	1.000	-	-		mtm8547
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12299
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1570
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	9.070