DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FDY and Serbp1

DIOPT Version :9

Sequence 1:	NP_001303579.2	Gene:	FDY / 8674077	FlyBaseID:	FBgn0265047	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_006236678.1	Gene:	Serbp1 / 246303	RGDID:	619907	Length:	407	Species:	Rattus norvegicus

Alignment Length:	468	Identity:	129/468 - (27%)
Similarity:	182/468 - (38%)	Gaps:	149/468 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NRYELLFMDDDD----------------SSGLEQPQIAAVVAAPKKPEPAKAPKVPKSKSEKENK 55
            ||::.||.|:.|                ..|:..|...:...|..:.....|.|..:.:|:|:.|
  Rat    15 NRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRK 79

  Fly    56 -PV-----VAGRKANT--PVAKNASPVKGGKGPAGGDVGRPKNPTANGANN------QGRFNNNQ 106
             |:     ||.:|..|  |||.....::        .|||..:....|...      :.|....:
  Rat    80 NPLPPSVGVADKKEETQPPVALKKEGIR--------RVGRRPDQQLQGDGKIIDRRPERRPPRER 136

  Fly   107 RY----GNKESIGEFGNELP--QRQFNNRDNRGPPR------VRSGEKF---GKREFDRQSGSDK 156
            |:    ..|...|||..:.|  :|....|...|..|      :..|:.|   |||||||.||||:
  Rat   137 RFEKPLEEKGEGGEFSVDRPIIERPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDR 201

  Fly   157 ------TGVKSIDKREGVGAHNWG--------SPK----------QDIEDLKTTGETSPQAEKKD 197
                  :|:|..|||.|.|:||||        |||          .|:|....|.|| |:.|:..
  Rat   202 SSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQKQISYNCSDLEQSNVTEET-PEGEEHP 265

  Fly   198 SANEQSADPAV-AAEEDESKQMTLDEWKALRDQ-RAKPNYNLRKAGEGAADNAEWKKMIVL--SK 258
            .|:.::.:..| ..:|:..|:||||||||:::: |||..:|:||..|||  :.:|||..||  ||
  Rat   266 VADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA--DGQWKKGFVLHKSK 328

  Fly   259 KKESNSEDELEYDPSLYPQRVGRLQRIVDIQFNFNDGRKGGFRKGTRRGAGPCEGGFRNDGPRGE 323
            .:|:::||.                 ::|..          |||.........|..|.:.|..|.
  Rat   329 SEEAHAEDS-----------------VMDHH----------FRKPANDITSQLEINFGDLGRPGR 366

  Fly   324 GGYRNDGPRGEGGYRNEGPRGEGYRNDGPREQGFRGPRFNNAPSNGYENRQDNNRFGEKRRSAEK 388
            ||....|.||.||..|.|.|.:                                     :.||..
  Rat   367 GGRGGRGGRGRGGRPNRGSRTD-------------------------------------KSSASA 394

  Fly   389 PLKVDDEAQFPTL 401
            | .|||...||.|
  Rat   395 P-DVDDPEAFPAL 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FDY	NP_001303579.2	HABP4_PAI-RBP1	144..242	CDD:335891	50/123 (41%)
FDY	NP_001303579.2	PRK11634	<308..368	CDD:236941	14/59 (24%)
Serbp1	XP_006236678.1	IHABP4_N	5..152	CDD:406560	31/144 (22%)
Serbp1	XP_006236678.1	HABP4_PAI-RBP1	189..312	CDD:398441	50/123 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I8380
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I4446
OMA	1	1.010	-	-		QHG48663
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002116
OrthoInspector	1	1.000	-	-		mtm9023
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12299
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1570
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070