Protein Alignment OtopLa and OtopLc

DIOPT Version :9

• Sequence 1: NP_001162676.1
• Gene: OtopLa / 8674066
• FlyBaseID: FBgn0259994
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: NP_001303575.1
• Gene: OtopLc / 7354434
• FlyBaseID: FBgn0259150
• Length: 1596
• Species: Drosophila melanogaster
• Alignment Length: 957
• Identity: 251/957 - (26%)
• Similarity: 382/957 - (39%)
• Gaps: 365/957 - (38%)

  Fly    46 QGDG-----YHTSPAHQRTPLVPHDLGEDFNLDFDDDFPIDARRPKNAKVCYTFKPNPNKYSFMP 105
            |.||     ||   :||.|                 ::|:.....:..:..:.:.|.|.
  Fly   847 QADGQLALMYH---SHQLT-----------------NYPVLPAIKRTHRPSFVYPPMPR------ 885

  Fly   106 AKITVQGTYETNPITGPIELWTSLFIVTSLVYAILLIVVCIAYVISDVTTHRLPVLYYETFFTYL 170
                             ::...:|..:.|.:|..||:|:.||:.:::|.:..:|..:||.::.||
  Fly   886 -----------------VKAGDALATLFSALYGKLLVVMGIAFPMAEVISTYIPPSFYEVYYLYL 933

  Fly   171 YGVSILFLLYVFCFLLQESSCCNGGNGGSKPK-PQPKEKKSKKAKNADPADSKDAKGSKDSGKAA 234
            |..|::|||:::..|:           ..:|| |.|....||.|..|...||.| :...||.
  Fly   934 YIGSMIFLLFMYATLI-----------WGRPKLPVPIASPSKSATKASGTDSMD-ESDTDSN--- 983

  Fly   235 KGAAYQHTLAKFLEAPVDAEVAVTPKNVRKRKTTHSDLTHGSFFLRVGAIAFGLGAMIYIGLEFG 299
               :..|.|..  ..||.....::|...|       |..:|||:||:||:|||:|:|||.|||||
  Fly   984 ---SVHHRLPP--PIPVRRPSLLSPLGRR-------DAHYGSFYLRMGAVAFGIGSMIYSGLEFG 1036

  Fly   300 SFFEIPFDSPCHHILIGVNPLLQMIFTFMQMYFIFM-NARLNIHRFKVIARFGLMHVVATNICVW 363
            .:||:..|:.||::|:.:.|..:|.|.|:||||||: |.::.::|:|:||||||||::.||:.||
  Fly  1037 QYFELNPDTKCHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVW 1101

  Fly   364 IRTLVKESLLEITIYHQKNEPEAGASSIAHSIRQHALRHAGTVLRTHAGPNSEFEVLDGEDILPK 428
            :..|::|:..||..::   .||.....|:|.|..|:..||                     |:..
  Fly  1102 LNVLIQETKHEILTFY---NPENRTLRISHRIPGHSRGHA---------------------IIQH 1142

  Fly   429 DVYKSDNVLSKLVRNTVDGISKSLGMGGDQALDSSTTSSSTTTTTRAPFTTPNYQWHSTTMARKL 493
            |                                       .|...|.|              |.|
  Fly  1143 D---------------------------------------PTAHLRVP--------------RGL 1154

  Fly   494 KKFITSATTAATTAAGSSSTASSTTTISPTISSTTIPSTTISSTTISSSTTFSPFSPSTTTTTTT 558
            |
  Fly  1155 K---------------------------------------------------------------- 1155

  Fly   559 TAAALNLETSGSESPFGGLQRILSSAAPPSLAPVDGFGSASAATPTSGSGAGSFVDSFLASTLSP 623
                                                                             
  Fly  1156 ----------------------------------------------------------------- 1155

  Fly   624 ASSTEGSASIMNNLFGQGPMENSFQTYTDLGHEEATGLVSFENLESLDNIYPAALSSNIGTLNST 688
                             ||.:                  .||
  Fly  1156 -----------------GPYQ------------------IFE----------------------- 1162

  Fly   689 ACGRIDIMGTIVYDSAPYLYPFIIEYSLIGAVVLYVMWKHIGR----YPGRMNDEDLEHRLEVML 749
             |.|.:|:||:|.|::|:|:|..||||||.|.:|||||:.|.|    .|.|.:          |:
  Fly  1163 -CRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPD----------MI 1216

  Fly   750 SRRAVAMAQQARSGRVDCVGSSKGLFFGLLLLVGALICLILFFVLVRHQQFSLLAIYLADASHCI 814
            |.   .|.:......|||..:.||||.|:|:||..:|.||:||||:...:|..:|:  .:.:.|.
  Fly  1217 SS---PMKRSPHHYSVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAV--TEVTICE 1276

  Fly   815 LMAF--AILAIIVGFIRVKNLKFRCEEQSNLNDILLRISAFGLFTYSVFSIIAGSLKVLESEPSL 877
            |:.:  |.:|.:||.|::::|::......:|:||||..:..|.|.|::|::|||.. .|.|: .:
  Fly  1277 LLIYGTATIATLVGMIQIRHLQYDAYRSFSLDDILLVGAQTGSFLYNIFTVIAGHF-TLRSD-DM 1339

  Fly   878 LVTTTGGVAVFQVILQLLFIADVSRRRVHLPEHDRSKPGRQIVTFLLICNVAMFAIYTFEAQKVF 942
            ||......::.|...|.:||.|.|||:...|||.|.||||:||||:|:.|:||:||.|.|..:..
  Fly  1340 LVPINALASIVQTACQTMFILDASRRQAVSPEHLRKKPGREIVTFMLVVNLAMWAISTLEKSRAE 1404

  Fly   943 ANPVQLEFYGFVPWSIIQRITLPLCIFHRFHSAVTLAEIWKTTYKAR 989
            ::|:||.|||...|:||..:::||.||:||||.|.|.||||..||.:
  Fly  1405 SHPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLK 1451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLa	NP_001162676.1	Otopetrin	278..>405	CDD:281218	59/127 (46%)
		Otopetrin	<679..972	CDD:281218	114/298 (38%)
OtopLc	NP_001303575.1	Otopetrin	1015..1434	CDD:281218	185/700 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I2171
eggNOG	1	0.900	-	-		E1_KOG4740
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D14847at7147
OrthoFinder	1	1.000	-	-		FOG0001932
OrthoInspector	1	1.000	-	-		mtm6364
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21522
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3542
SonicParanoid	1	1.000	-	-		X278
	9	8.950