Protein Alignment OtopLa and otop2

DIOPT Version :10

• Sequence 1: NP_001162676.1
• Gene: OtopLa / 8674066
• FlyBaseID: FBgn0259994
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: XP_001338079.4
• Gene: otop2 / 494472
• ZFINID: ZDB-GENE-050104-2
• Length: 572
• Species: Danio rerio
• Alignment Length: 374
• Identity: 95/374 - (25%)
• Similarity: 150/374 - (40%)
• Gaps: 86/374 - (22%)

  Fly   668 ESL-DNIYPAALSSNIGTLNSTACGR------------IDIMGTIVYDSAPYLYPFIIEYSLIGA 719
            ||| ..:.|....:|..:.|.|..||            .|:.....|    |||||.|||||..:
Zfish   221 ESLHQTVAPVKPPTNNNSYNDTLDGRAAASECECLHNMCDLFEKAYY----YLYPFNIEYSLFAS 281

  Fly   720 VVLYVMWKHIGRYPGRMNDEDLEHRLEVMLSRRAVAMAQQARSGRVDCVGSSKGLFFGLLLLVGA 784
            .:.|||||::||   :|:|.. .|:|...|....|                  |...||::||..
Zfish   282 AMTYVMWKNVGR---KMDDHH-SHKLHFSLWDVLV------------------GPLAGLIVLVAG 324

  Fly   785 LICLILFFVLV-----RHQQFSLLAIYLADASHCILMAFAILAIIVGFIRVKNLKFRCEEQSNLN 844
            |...:::.|.|     :.::.:|:..|:.:....:||:.:.||..:.|...|..:...:..:...
Zfish   325 LATFVVYEVDVSKDDPKKKEEALIMHYIMNIVAVLLMSSSALAGCILFRMDKREQVSGKNPTRSL 389

  Fly   845 DILLRISA-FGLFTYSVFSIIAGSLKVLESEPSLLVTTTGGVAVFQVILQLLFI----------- 897
            |:.|.:.| .|.|....|:|:|.....::...:.|......:.|.::.:|..|:
Zfish   390 DVGLLVGASLGQFLICYFTIVAVLASGVQGHTNGLNLACAMLTVIELCIQNAFLIKGLHREPFKE 454

  Fly   898 ---------------ADVSRRRVHL-PEHDRSKP-----GR---------QIVTFLLICNVAMFA 932
                           .|..||...: |.|....|     ||         :|..|||:|||.::.
Zfish   455 TEVATVFANVMAVKERDPERRSSSIVPAHTLPIPLTLLQGRMSWKRRVLKEICAFLLLCNVTLWI 519

  Fly   933 IYTFEAQKVFANPVQLEFYGFVPWSIIQRITLPLCIFHRFHSAVTLAEI 981
            |..|.|:..|.|.|..:.|.|..|:.:..|.:|..||:|.||..:|.|:
Zfish   520 IPAFGARPQFDNTVGPDVYEFQTWAAVVNIGMPFGIFYRMHSVASLFEV 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLa	NP_001162676.1	Otopetrin	278..>425	CDD:460840
		Otopetrin	<673..972	CDD:460840	87/357 (24%)
otop2	XP_001338079.4	Otopetrin	133..558	CDD:460840	90/362 (25%)