DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment OtopLa and Otop3

DIOPT Version :9

Sequence 1:	NP_001162676.1	Gene:	OtopLa / 8674066	FlyBaseID:	FBgn0259994	Length:	991	Species:	Drosophila melanogaster
Sequence 2:	XP_038941598.1	Gene:	Otop3 / 287821	RGDID:	1306663	Length:	578	Species:	Rattus norvegicus

Alignment Length:	360	Identity:	92/360 - (25%)
Similarity:	145/360 - (40%)	Gaps:	106/360 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   685 LNSTACGRIDIMGTIVYDSAPYLYPFIIEYSLIGAVVLYVMWKHIGR--------YPGRMNDEDL 741
            ||:|.| .:...|.::      ||||..||.||...||:||||::||        :|.|.
  Rat   260 LNATVC-EVFRKGFLM------LYPFSTEYCLICCAVLFVMWKNVGRSLAAHSGAHPNRP----- 312

  Fly   742 EHRLEVMLSRRAVAMAQQARSGRVDCVGSSKGLFFGLLLLVGALICLILFFVL------VRHQQF 800
            ..||.                      |:..|...|||.|| |.:|:.:.|.:      :..|.|
  Rat   313 PFRLH----------------------GAIFGPLLGLLALV-AGVCVFVLFQIEASGPDIARQYF 354

  Fly   801 SL-LAIYLADASHCIL--MAFAILA-IIVGFIRVKNLKFRCEEQSNLNDILLRISAFGLFTYSVF 861
            :| .|.|:|     :|  |:.|.|| ..:..:..:.|........:|:.:||..:|.|....:.|
  Rat   355 TLYYAFYVA-----VLPTMSLACLAGTAIHGLEERELDTLKNPTRSLDVVLLMGAALGQMGIAYF 414

  Fly   862 SIIAGSLKVLESEP----SLLVTTTGGVAVFQVILQLLFIADVSRRR---------------VHL 907
            ||:|    ::.::|    :.|:.....:.:.|.|.|.|||.:...||               :.|
  Rat   415 SIVA----IVATQPHQLLNQLILAYSLLLILQHITQNLFIIEGLHRRPLWEPVISGVPEKQDIEL 475

  Fly   908 PE--------HDRSKPGR-----------------QIVTFLLICNVAMFAIYTFEAQKVFANPVQ 947
            |.        .|..:..|                 :|..||::||:.::.:..|.....|.|.::
  Rat   476 PRRGSLRELGQDLRRASRAYIHSFSHLNWKRRMLKEISLFLILCNITLWMMPAFGIHPEFENGLE 540

  Fly   948 LEFYGFVPWSIIQRITLPLCIFHRFHSAVTLAEIW 982
            .:|||:..|..|....|||.:|:|.||...|.|::
  Rat   541 KDFYGYRTWFTIVNFGLPLGVFYRMHSVGGLVEVY 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OtopLa	NP_001162676.1	Otopetrin	278..>405	CDD:281218
OtopLa	NP_001162676.1	Otopetrin	<679..972	CDD:281218	87/348 (25%)
Otop3	XP_038941598.1	Otopetrin	149..564	CDD:397346	87/347 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4035
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21522
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.160