Protein Alignment OtopLa and otop2

DIOPT Version :10

• Sequence 1: NP_001162676.1
• Gene: OtopLa / 8674066
• FlyBaseID: FBgn0259994
• Length: 991
• Species: Drosophila melanogaster
• Sequence 2: XP_017944835.2
• Gene: otop2 / 100496174
• XenbaseID: XB-GENE-6045877
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 356
• Identity: 83/356 - (23%)
• Similarity: 134/356 - (37%)
• Gaps: 113/356 - (31%)

  Fly   706 YLYPFIIEYSLIGAVVLYVMWKHIGRYPGRMNDEDLEHRLEVMLSRRAVAMAQQARSGRVDCVGS 770
            |||||.|||||..:.:.|||||::||.  .......:|:.:
 Frog   270 YLYPFNIEYSLFASAMSYVMWKNVGRV--MSGHHHTQHKFK------------------------ 308

  Fly   771 SKGLFFGLLLLVGALICLILFFVL---------VRHQQFSLLAIYLADASHCILMAFAILA--II 824
            ::.||.||:..:|..:..:..|::         .|.|..::  .|:.:.:...||:...||  ||
 Frog   309 TRNLFVGLICGIGVFVAGLGVFIVYKIEVDVEETRSQAITM--FYIFNITALSLMSVVSLAGTII 371

  Fly   825 VGFIRVKNLKFRCEEQSNLNDILLRISAFGLFTYSVFSIIA-------GSLKVLESEPSLLVTTT 882
            ..|.: :::.........|:.:||..:|.|.:..|.|||:|       |.|..|....:||:
 Frog   372 YRFYK-RDMDNHKNPTRTLDVVLLLGAALGQYCISFFSIVAMVALQPGGQLHTLILVNALLL--- 432

  Fly   883 GGVAVFQVILQLLFIADVSRRRVHLPEHD------------------------------------ 911
                :.|..:|..||.:...|:.|...|.
 Frog   433 ----IVQHTIQNTFIIEGLHRQPHANSHPAADLQEKDQPPHVYINPAATVSHSDHSPSSHEKHEH 493

  Fly   912 ----------------------RSKPGRQIVTFLLICNVAMFAIYTFEAQKVFANPVQLEFYGFV 954
                                  |.|..::|..|||:.|:..:.:..|.|:..|.|.::|.|||:.
 Frog   494 ELETKHHGTPTGFPECHSKSDWRRKALKEISLFLLVSNIIFWIMPAFGARPQFDNRLELNFYGYT 558

  Fly   955 PWSIIQRITLPLCIFHRFHSAVTLAEIWKTT 985
             |..|..|.||..||:|.|:..:|.|::..|
 Frog   559 -WVAIVNIGLPFGIFYRMHAIASLVEVYIMT 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLa	NP_001162676.1	Otopetrin	278..>425	CDD:460840
		Otopetrin	<673..972	CDD:460840	78/341 (23%)
otop2	XP_017944835.2	Otopetrin	134..574	CDD:460840	78/340 (23%)