Protein Alignment mgl and ImpE1

DIOPT Version :10

• Sequence 1: NP_572563.3
• Gene: mgl / 8674055
• FlyBaseID: FBgn0261260
• Length: 4769
• Species: Drosophila melanogaster
• Sequence 2: NP_524849.2
• Gene: ImpE1 / 45879
• FlyBaseID: FBgn0001253
• Length: 1616
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 78/263 - (29%)
• Similarity: 106/263 - (40%)
• Gaps: 65/263 - (24%)

  Fly  3877 CGNNRCIPKQWMCDFADD---------CGDASDENEAVCKGRYRECSESEFRC-GNGKCISSRWQ 3931
            |.::|      .|..||.         |..|:.|..:.|......||...|:| .:|.|||..:.
  Fly  1365 CSSDR------QCQLADPHTVCNRRGVCDCAAGEEGSQCSAERTGCSPGTFQCRSSGVCISWFFV 1423

  Fly  3932 CDHEDDCGDNSDEMHCE-----GYQCKNGTFQC-ASGHCIASYFRCDGDRDCRDMSDEVGCPPRF 3990
            ||...||.|.||| .|.     ...|...:|:| .||.||:....|||.|.|....||:||....
  Fly  1424 CDGRADCNDASDE-ECTHNARLNQTCPTESFRCQRSGRCISRAALCDGRRQCPHGEDELGCDGSV 1487

  Fly  3991 PGGRYCPESRFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVC----------------------- 4032
            .||..|||..|:|.:..|:...:.|:....|.|||||.|.:|
  Fly  1488 KGGNACPEHTFRCGSGECLPEYEYCNAIVSCKDGSDEPPHLCGSRALPNLFMRLIEAGGLLGGGR 1552

  Fly  4033 --SDFNCDTLRRFQCSNERCVARYQICDGVDNCGDGSDENNMTLC-------------ASKQKPC 4082
              :|..|.    .:|||..|.:...:|.|.|.||||:||...::|             .::|:|.
  Fly  1553 READAYCP----HRCSNGLCRSTAIVCSGRDGCGDGTDEQTCSVCRCPAPTAASLPAFLARQRPM 1613

  Fly  4083 DLY 4085
            .|:
  Fly  1614 PLW 1616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mgl	NP_572563.3	LDLa	157..189	CDD:238060
		LDLa	204..236	CDD:238060
		LDLa	292..327	CDD:238060
		LDLa	332..366	CDD:238060
		LDLa	371..412	CDD:238060
		vWFA	<447..488	CDD:469594
		YncE	<492..634	CDD:442618
		NHL	573..>716	CDD:302697
		NHL repeat	573..610	CDD:271320
		NHL repeat	616..654	CDD:271320
		NHL repeat	657..693	CDD:271320
		FXa_inhibition	763..805	CDD:464251
		YvrE	854..>992	CDD:442613
		LY	922..964	CDD:214531
		LY	973..1007	CDD:214531
		Ldl_recept_a	1188..1223	CDD:395011
		LDLa	1227..1259	CDD:197566
		LDLa	1268..1303	CDD:238060
		LDLa	1308..1343	CDD:238060
		LDLa	1356..1387	CDD:238060
		LDLa	1391..1423	CDD:197566
		LDLa	1435..1469	CDD:197566
		FXa_inhibition	1522..1553	CDD:464251
		LY	1625..1665	CDD:214531
		LY	1667..1711	CDD:214531
		Ldl_recept_b	1690..1729	CDD:459654
		LY	1712..1754	CDD:214531
		LY	1986..2037	CDD:214531
		FXa_inhibition	2151..>2179	CDD:464251
		LY	2259..2305	CDD:214531
		Ldl_recept_b	2326..2366	CDD:459654
		LY	2352..2392	CDD:214531
		NHL	2579..>2711	CDD:302697
		NHL repeat	2593..2622	CDD:271320
		NHL repeat	2634..2678	CDD:271320
		LY	2671..2713	CDD:214531
		LDLa	2867..2901	CDD:238060
		LDLa	2906..2941	CDD:238060
		LDLa	2950..2983	CDD:238060
		LDLa	3034..3066	CDD:197566
		LDLa	3080..3115	CDD:197566
		LDLa	3128..3159	CDD:238060
		LDLa	3170..3204	CDD:238060
		LDLa	3210..3242	CDD:197566
		FXa_inhibition	3259..3287	CDD:464251
		FXa_inhibition	3293..3329	CDD:464251
		LY	3362..3394	CDD:214531
		LY	3406..3448	CDD:214531
		Ldl_recept_b	3468..3511	CDD:459654
		LY	3498..3536	CDD:214531
		LY	3536..3578	CDD:214531
		FXa_inhibition	3607..3659	CDD:464251
		LDLa	3663..3696	CDD:238060
		LDLa	3705..3739	CDD:238060
		LDLa	3743..3775	CDD:197566
		LDLa	3784..3817	CDD:197566
		LDLa	3827..3861	CDD:197566
		LDLa	3871..3901	CDD:197566	7/32 (22%)
		LDLa	3913..3947	CDD:238060	16/34 (47%)
		LDLa	3952..3986	CDD:238060	14/34 (41%)
		LDLa	3996..4027	CDD:197566	11/30 (37%)
		LDLa	4043..4071	CDD:238060	13/27 (48%)
		LDLa	4086..4117	CDD:238060	78/263 (30%)
		EGF_CA	4163..4194	CDD:214542
NHL	4276..>4426	CDD:302697
NHL repeat	4291..4336	CDD:271320
Ldl_recept_b	4350..4391	CDD:459654
LY	4374..4417	CDD:214531
NHL repeat	4376..4422	CDD:271320
ImpE1	NP_524849.2	EB	75..131	CDD:460294
		rne	<795..981	CDD:236766
		LDLa	1404..1437	CDD:238060	16/33 (48%)
		LDLa	1448..1483	CDD:238060	14/34 (41%)
		LDLa	1493..1524	CDD:238060	11/30 (37%)