| Sequence 1: | NP_001096924.2 | Gene: | mgl / 8674055 | FlyBaseID: | FBgn0261260 | Length: | 4769 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_005267567.1 | Gene: | LRP10 / 26020 | HGNCID: | 14553 | Length: | 721 | Species: | Homo sapiens |
| Alignment Length: | 468 | Identity: | 116/468 - (24%) |
|---|---|---|---|
| Similarity: | 142/468 - (30%) | Gaps: | 186/468 - (39%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3615 SHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFYLARDMKTCVANCTAGQHLCGGRDEKCIP 3679
Fly 3680 WFWK----CDGEKDCKDGSDEP--ATC-------------------------------------A 3701
Fly 3702 PRH--------CRAGTFQCKNTNCTPSATICDGVDDCGDRSDEQNC--------------DLPC- 3743
Fly 3744 -PLSDF--KCKSSGRCILDS--------WRCD------------------GDA-DCKDGSDEDPA 3778
Fly 3779 VCFKRTCDPKTEFS----------------------CKNGR-----------CIPQLWMCDFDND 3810
Fly 3811 CGDDSDEPAYMCRQRNCTTGWQRCPGQSNYRCIPKWLFCDGKDDCRDNSDELPENCPKCNPETDF 3875
Fly 3876 KC------GNNRCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNGKCISSRWQCDH 3934
Fly 3935 EDDCGDNSDEMHC 3947 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| mgl | NP_001096924.2 | LDLa | 157..189 | CDD:238060 | |
| LDLa | 204..236 | CDD:238060 | |||
| LDLa | 292..327 | CDD:238060 | |||
| LDLa | 332..366 | CDD:238060 | |||
| LDLa | 371..412 | CDD:238060 | |||
| vWFA | <447..488 | CDD:294047 | |||
| NHL | 573..>716 | CDD:302697 | |||
| NHL repeat | 573..610 | CDD:271320 | |||
| NHL repeat | 616..654 | CDD:271320 | |||
| NHL repeat | 657..693 | CDD:271320 | |||
| FXa_inhibition | 763..805 | CDD:291342 | |||
| LY | 922..964 | CDD:214531 | |||
| LY | 973..1007 | CDD:214531 | |||
| Ldl_recept_a | 1188..1223 | CDD:278486 | |||
| LDLa | 1227..1259 | CDD:197566 | |||
| LDLa | 1268..1303 | CDD:238060 | |||
| LDLa | 1308..1343 | CDD:238060 | |||
| LDLa | 1356..1387 | CDD:238060 | |||
| LDLa | 1391..1423 | CDD:197566 | |||
| LDLa | 1435..1469 | CDD:197566 | |||
| FXa_inhibition | 1478..1513 | CDD:291342 | |||
| FXa_inhibition | 1522..1553 | CDD:291342 | |||
| LY | 1625..1665 | CDD:214531 | |||
| LY | 1667..1711 | CDD:214531 | |||
| Ldl_recept_b | 1690..1728 | CDD:278487 | |||
| LY | 1712..1754 | CDD:214531 | |||
| LY | 1986..2037 | CDD:214531 | |||
| FXa_inhibition | 2151..>2179 | CDD:291342 | |||
| LY | 2259..2305 | CDD:214531 | |||
| Ldl_recept_b | 2326..2366 | CDD:278487 | |||
| LY | 2352..2392 | CDD:214531 | |||
| NHL | 2579..>2711 | CDD:302697 | |||
| NHL repeat | 2593..2622 | CDD:271320 | |||
| NHL repeat | 2634..2678 | CDD:271320 | |||
| LY | 2671..2713 | CDD:214531 | |||
| LDLa | 2867..2901 | CDD:238060 | |||
| LDLa | 2906..2941 | CDD:238060 | |||
| LDLa | 2950..2983 | CDD:238060 | |||
| LDLa | 3034..3066 | CDD:197566 | |||
| LDLa | 3080..3115 | CDD:197566 | |||
| LDLa | 3128..3159 | CDD:238060 | |||
| LDLa | 3170..3204 | CDD:238060 | |||
| LDLa | 3210..3242 | CDD:197566 | |||
| cEGF | 3269..3292 | CDD:289433 | |||
| vWFA | <3284..3324 | CDD:294047 | |||
| LY | 3362..3394 | CDD:214531 | |||
| LY | 3406..3448 | CDD:214531 | |||
| LY | 3498..3536 | CDD:214531 | |||
| LY | 3536..3578 | CDD:214531 | |||
| FXa_inhibition | 3607..3659 | CDD:291342 | 8/43 (19%) | ||
| LDLa | 3663..3696 | CDD:238060 | 7/36 (19%) | ||
| LDLa | 3705..3739 | CDD:238060 | 17/33 (52%) | ||
| LDLa | 3743..3775 | CDD:197566 | 15/62 (24%) | ||
| LDLa | 3784..3817 | CDD:197566 | 13/65 (20%) | ||
| LDLa | 3827..3861 | CDD:197566 | 9/33 (27%) | ||
| LDLa | 3871..3901 | CDD:197566 | 8/35 (23%) | ||
| LDLa | 3913..3947 | CDD:238060 | 15/33 (45%) | ||
| LDLa | 3952..3986 | CDD:238060 | |||
| LDLa | 3996..4027 | CDD:197566 | |||
| LDLa | 4043..4071 | CDD:238060 | |||
| LDLa | 4086..4117 | CDD:238060 | |||
| EGF_CA | 4163..4194 | CDD:214542 | |||
| NHL | 4276..>4426 | CDD:302697 | |||
| NHL repeat | 4291..4336 | CDD:271320 | |||
| Ldl_recept_b | 4350..4390 | CDD:278487 | |||
| NHL repeat | 4376..4422 | CDD:271320 | |||
| LRP10 | XP_005267567.1 | CUB | 34..134 | CDD:238001 | 17/114 (15%) |
| LDLa | 148..182 | CDD:238060 | 17/33 (52%) | ||
| CUB | 200..310 | CDD:238001 | 22/112 (20%) | ||
| LDLa | <338..361 | CDD:238060 | 12/39 (31%) | ||
| LDLa | 407..441 | CDD:238060 | 15/33 (45%) | ||
| PRK04654 | <581..683 | CDD:135173 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1215 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||