Protein Alignment Pif1A and Jakmip1

DIOPT Version :9

• Sequence 1: NP_001189195.2
• Gene: Pif1A / 8674049
• FlyBaseID: FBgn0261015
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_011239086.1
• Gene: Jakmip1 / 76071
• MGIID: 1923321
• Length: 851
• Species: Mus musculus
• Alignment Length: 1147
• Identity: 247/1147 - (21%)
• Similarity: 416/1147 - (36%)
• Gaps: 355/1147 - (30%)

  Fly    58 MAKNKLKRKKKLSSSLTSVGDTVNQEKRTRIEGIQLHCRGKLRPKETQSFEAEKGPSAGSQKQLG 122
            |:|....:..|..:...|| ...|:|.|.::..||:            .|:.||......:::|.
Mouse     1 MSKKGRSKGDKPEAETDSV-QMANEELRAKLTNIQI------------EFQQEKSKVGKLRERLQ 52

  Fly   123 KAEKDRERPVIIGGVTTTNVIAAPPQRIKRKLQENMDTIQKLNA-LTEQLRLEVNELKSSLIT-- 184
            :|:.:||                      ::.:.:...|.:|.| |.|:...|:..|:.:||.
Mouse    53 EAKLERE----------------------QEQRRHTAYISELKAKLHEEKTKELQALREALIRQH 95

  Fly   185 ERGAVRALRAQNDADSRRWKSEVKKLQHTLEMAK--KSNGIKKAIESGPESSGAHVTADGLINYE 247
            |:.|.|..:.:        :.|:::||.||.:.:  .::.:|.|:.:..... |..|.||    |
Mouse    96 EQEAARTAKIK--------EGELQRLQATLNVLRDGAADKVKTALLADAREE-ARRTFDG----E 147

  Fly   248 IQRLTNEIAVLKEANRNKEEKTQIMGQADRLKAADMRQLKNAYENRLTHIQKSAKIEITRLLEEI 312
            .|||..||..||.|.:..||......|||:.||||:|....|:::.:..|::..:.:|.||::||
Mouse   148 RQRLQQEILELKAARKQAEEALSNCMQADKAKAADLRAAYQAHQDEVHRIKRECERDIRRLMDEI 212

  Fly   313 KTKERNIGQLRKDL--LALQSPKKLKQNEAKVPATTKPKTNPNETSQKPKKPTTKAAGETKAKTE 375
            |.|||.|..|.|:|  ...|:.:.|.|.||......:.|......| .||:......|: .|:..
Mouse   213 KGKERVILALEKELGVQTGQTQRLLLQKEALDEQLVQVKEAERHHS-SPKRELPPGIGD-MAELM 275

  Fly   376 PDTDTDISEQNPIRQAQVTPEITQLKNIELINNTKNAHKSALEMRTTMKSSQPNGLDDAPTRMRA 440
            ...|..:.|::..|        .|||..||     |:....||.|.|:.:.:.|
Mouse   276 GGQDQHMDERDVRR--------FQLKIAEL-----NSVIRKLEDRNTLLADERN----------- 316

  Fly   441 PDEMRATTWMTTLVGSNCHSHSHSHPAVAKSKDPNSDTDSALSSAPPSISPQPPSSGSDSGVIWQ 505
                       .|:..:..:.....|.|.|:|..|...:..|.|
Mouse   317 -----------ELLKRSRETEVQLKPLVEKNKRMNKKNEELLHS--------------------- 349

  Fly   506 TLQDLDKLQKEAEMYQKENERLQTEVQLMKQELDAAEKAAISRAKKQAQIGELMQRIKELEEMQS 570
                :.:::::.:...:||..       ||::|.|  :|::.|                    .:
Mouse   350 ----IQRMEEKLKSLTRENVE-------MKEKLSA--QASLKR--------------------HT 381

  Fly   571 SLEDEASELREQNELLEFRILELEDDSDKMESTCEGHCQSLQDLLEQSAQRLEDRDKRCLQQLLQ 635
            ||.| .|..|::.|:...|:..||.             |.:.|.|....:||. |.||...:.|:
Mouse   382 SLND-LSLTRDEQEIEFLRLQVLEQ-------------QHVIDDLSLERERLL-RSKRHRGKSLK 431

  Fly   636 CVQQLDLDTMMPGDQNRTETPKRHNSTHSHSHSHSHSQSHNHRIVATVQPYSNCATPTAPPTPSK 700
            ..::..::|....|:...:             |.:.|::          .|:...|...|.||.:
Mouse   432 PPKKHVVETFFGFDEESVD-------------SETLSET----------SYNTDRTDRTPATPEE 473

  Fly   701 RHCNQVSSWQSSSLSESGVFVECDLLSNPNPIGHPHLQFYQERLEQLEGKLLIYESSGETQARHL 765
                        .|.|:....|.||
Mouse   474 ------------DLDETTTREEADL---------------------------------------- 486

  Fly   766 AQRLQRELQLEKDLKELADRVELLIEQNAQLEEAKCEFEEAENDTRLHLQ----RNEVELEILRQ 826
                 |..||.::.:.|.....||.||.....:|     |.|..||..||    |.:.::|.|.:
Mouse   487 -----RFCQLTREYQALQRAYALLQEQVGGTLDA-----EREARTREQLQADLLRCQAKIEDLEK 541

  Fly   827 RNVELEFGKEALGAKYQDC----RAEVLI-LREDLAAAETQLEHLQAERKQARKELQDLRRSLPL 886
            ..||          |.||.    ..:||: ..:||.   .::..|:.|..|.:.|:||.:....
Mouse   542 LLVE----------KGQDAAWVEEKQVLMRTNQDLL---EKIYRLEMEENQLKSEMQDAKDQNE- 592

  Fly   887 LLIFRLLSLAKMGNEESSPGGSPRL-------SSGYTSSIHQDRDFSAKIQTTEFDLGQAGFTDS 944
            ||.||:|.|.:  .|..||..:.::       ||......||:......|.....:|...|  |:
Mouse   593 LLEFRVLELEE--RERRSPAFNLQITTFPENNSSALQLFCHQEGVKGVNISELMKNLDILG--DN 653

  Fly   945 GEEREIVYLKEEVKSLRS----QLKELNARHYEAMETA-DSHWVDLEQQYKEREEAQQAKEASLK 1004
            |..|.    :|:|..:::    .|.|...:..|..|.| ....:|||   ||:::..:.| ..|:
Mouse   654 GNLRN----EEQVAVIQAGTVLALCEKWLKQIEGTEAALTQKMMDLE---KEKDQFSRQK-GYLE 710

  Fly  1005 QKIAQLQDCLREDSRAATEKIQQLEEGELSLKSCLVRMTKEHRDLLTENRTLQCSLESLMAKMEK 1069
            |::...::.|.:......||||.||
Mouse   711 QELDYRKEALDQAYLVGPEKIQDLE---------------------------------------- 735

  Fly  1070 EAEHKMPLTEALENE--RRKTQAL----MDDLIFA-KKVQQNTEDQLRQETDALRTQIFNIKKDY 1127
                 ..|..||:.|  ||.::||    .:||..| :||::    ||.:::....:||...:.:.
Mouse   736 -----ATLYNALQQEPGRRASEALSASQREDLQAAVEKVRR----QLLRQSREFDSQILRERMEL 791

  Fly  1128 LHIEVTNGELKEEVGTLENKIRQMENQMRDSEERARCLEDEL 1169
            |.      :.::::..:|.|:.....|:::.||:...|..||
Mouse   792 LQ------QAQQKIREMEGKLELQRRQLKELEEKDPLLNLEL 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pif1A	NP_001189195.2	JAKMIP_CC3	<156..282	CDD:292653	39/130 (30%)
		JAKMIP_CC3	<516..595	CDD:292653	16/78 (21%)
Jakmip1	XP_011239086.1	SMC_prok_A	56..>363	CDD:274009	92/403 (23%)
		JAKMIP_CC3	415..612	CDD:374316	62/298 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002005
OrthoInspector	1	1.000	-	-		oto94677
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000