Protein Alignment Pif1A and Jakmip2

DIOPT Version :10

• Sequence 1: NP_001189195.2
• Gene: Pif1A / 8674049
• FlyBaseID: FBgn0261015
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_038952785.1
• Gene: Jakmip2 / 307479
• RGDID: 1559742
• Length: 831
• Species: Rattus norvegicus
• Alignment Length: 995
• Identity: 198/995 - (19%)
• Similarity: 361/995 - (36%)
• Gaps: 314/995 - (31%)

  Fly    60 KNKLKRKKKLSSSLTSVGDTVNQEKRTRIEGIQLHCRGKLRPKETQSFEAEKGPSAGSQKQLGKA 124
            :||.::.:.|..:|    ...|::.||::..||:....:  ..:....|.||...|...::|
  Rat     6 RNKGEKPEALIVAL----QAANEDLRTKLTDIQIELHQE--KSKVSKLEREKTQEAKRIREL--- 61

  Fly   125 EKDRERPVIIGGVTTTNVIAAPPQRIKRKLQENMDTIQKLNALTEQL-RLEVNELKSSLITERGA 188
             :.|:..|::             ..:|.||.|  :.:::|.|:.|.| :....|:..::....|.
  Rat    62 -EQRKHTVLV-------------TELKAKLHE--EKMKELQAVRENLIKQHEQEMSRTVKVRDGE 110

  Fly   189 VR----ALRAQNDADSRRWKSEVKKLQHTLEMAKKSNGIKKAIESGPESSGAHVTADGLINYEIQ 249
            ::    ||.|..|..|.:.::.:     |:|..:::   :|..::                 |..
  Rat   111 IQRLKSALCALRDGSSDKVRTAL-----TIEAREEA---RKQFDA-----------------ERL 150

  Fly   250 RLTNEIAVLKEANRNKEEKTQIMGQADRLKAADMRQLKNAYENRLTHIQKSAKIEITRLLEEIKT 314
            :|..||..||.|.:..:|....|.|||::||.|:|....:::..::.|:..::.:|.||::|||.
  Rat   151 KLLQEITDLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKA 215

  Fly   315 KERNIGQLRKDL---------LALQ-------------------SPKK----------------- 334
            |:|.|..|.|:|         |.||                   |||:
  Rat   216 KDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPD 280

  Fly   335 LKQNE---AKVPATTKPKTNPNETSQKPKKPTTKAAGETKAKTEPDTDTDISEQNPIRQAQVTPE 396
            |::|:   |::.||.:...:.|......:....|...||:.:.:|     :.|:|.....:....
  Rat   281 LRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKP-----LLERNKCLAKRNDEL 340

  Fly   397 ITQLKNIELINNTKNAHKSALEMRTTMKSSQP-------NGLDDAPTRMRAP------------- 441
            :..|:.:|  ...|...|...|||..:.|..|       |.||.|.......
  Rat   341 MVSLQRME--EKLKAITKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNII 403

  Fly   442 DEMRATTWMTTLVGSNCHSHSHS-------HPAVAKSKDPNSDTDSALSSAPPSISPQPPSSGSD 499
            ||:  |.....|:....|..|..       .|.:...:|......|:::|.....:|..|....|
  Rat   404 DEL--TRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMTSFRTDRTPATPDDDLD 466

  Fly   500 SGVI--------------WQTLQDLDKLQKE-------AEMYQKENERLQTEVQLMK---QELDA 540
            ..:.              :|.||....|.:|       ||...|..|:||.||...:   ::|:|
  Rat   467 ESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYRAKIEDLEA 531

  Fly   541 --AEKAAISRAKKQAQI-----GELMQRIKELEEMQSSLEDEASELREQNELLEFRILELEDD-- 596
              |:|...|...:..|:     .||:::|::.|.....|:.|..:.|:||||||||.||||:.
  Rat   532 TLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERER 596

  Fly   597 ------------SDKMESTCEGHC--QSLQDLLEQSAQRLEDRDKRCLQQLLQCVQQLDLDTMMP 647
                        ||.: |..:.:|  :.::|:                 .:...::|||:    .
  Rat   597 RSPPFNLQIHPFSDGV-SALQIYCMKEGVKDV-----------------NIPDLIKQLDI----L 639

  Fly   648 GDQNRTETPKRHNSTHSHSHSHSHSQSHNHRIVATVQPYSNCATPTAPPTPSKRHCNQVSSWQSS 712
            ||..                                               :.|:..||:..|:|
  Rat   640 GDNG-----------------------------------------------NLRNEEQVAIIQAS 657

  Fly   713 SLSESGVFVECDLLSNPNPIGHPHLQFYQERLEQLEGKLLIYESSGETQARHLAQRLQRELQLEK 777
            ::                      |...::.::|:|         |...|.|     |:.::||.
  Rat   658 TV----------------------LSLAEKWIQQIE---------GAEAALH-----QKMMELES 686

  Fly   778 DLKELADRVELLIEQNAQLEEAKCEFEEAENDTRLHLQRNEVELEILRQRNVELEFGKEALGAKY 842
            |:::..       :....|||.....::|.:...:.:|..|..|....|:...::||:.....:.
  Rat   687 DMEQFC-------KIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSDKQQ 744

  Fly   843 QDCRAEVLILRE---------DLAAAETQLEHLQAERKQARKELQDLRRSLPLLLIFRLLSLAKM 898
            ::.|..|..||.         |....:.::|.||    ||.:.::||.....:.. .::..|.:.
  Rat   745 EELRTAVEKLRRQMLRKSREYDCQILQERMELLQ----QAHQRIRDLEDKTDIQK-RQIKDLEEK 804

  Fly   899 GNEESSPGGSPRLSSGYTSS 918
            .|:|.  |..|:.::.:..|
  Rat   805 KNQEL--GSYPKKANAFKPS 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pif1A	NP_001189195.2	JAKMIP_CC3	<516..595	CDD:464986	33/95 (35%)
		Smc	<741..>1156	CDD:440809	37/187 (20%)
Jakmip2	XP_038952785.1	Smc	19..>600	CDD:440809	142/639 (22%)
		JAKMIP_CC3	409..602	CDD:464986	48/192 (25%)
		Smc	<646..>809	CDD:440809	39/210 (19%)