Protein Alignment Pif1A and jakmip3

DIOPT Version :10

• Sequence 1: NP_001189195.2
• Gene: Pif1A / 8674049
• FlyBaseID: FBgn0261015
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: XP_031762293.1
• Gene: jakmip3 / 100496365
• XenbaseID: XB-GENE-982110
• Length: 842
• Species: Xenopus tropicalis
• Alignment Length: 951
• Identity: 203/951 - (21%)
• Similarity: 358/951 - (37%)
• Gaps: 289/951 - (30%)

  Fly   111 KGPSAGSQKQLGKAEKDRERPVIIGGVTTTNVIAAPPQRIKRKLQENMDTIQKL----NALTEQL 171
            ||..|.:...|..|.:|               :.|....|:.:||:....:.||    |...:|:
 Frog    11 KGDKADASASLQAANED---------------LRAKLTDIQIELQQEKSKVSKLEREKNQEIKQI 60

  Fly   172 R--------LEVNELKSSLITERGAVRALRAQNDADSRRWKSEVKKLQHTLEMAKKSN----GIK 224
            |        :.:.|||:.|..|:  ::.|:|..:|..|:.:||   |...:::....|    .|.
 Frog    61 REHEQHKNIVLITELKAKLHEEK--MKELQAVREALLRQHESE---LFRVIKIKDNDNQRLQAIV 120

  Fly   225 KAIESG-PES------SGAHVTADGLINYEIQRLTNEIAVLKEANRNKEEKTQIMGQADRLKAAD 282
            .|:..| ||.      |.|...|..:.::|..::..||..||.|.|..||...::.|||::|||:
 Frog   121 NALRDGAPEKVKTVLFSEAKEEAKKVFDFEKIKMQQEIFELKGAKRQMEEALTVVMQADKMKAAE 185

  Fly   283 MRQLKNAYENRLTHIQKSAKIEITRLLEEIKTKERNIGQLRKDLLALQS--PKKLK-QNEAKVPA 344
            :|.:.:.::..::.|::..:.||.||::|||.|:|.:..|.|: |.:||  .::|: |.||....
 Frog   186 IRSIYHLHQEEISKIKRECEREIRRLMDEIKLKDRAVNLLEKE-LGVQSGHAQRLQLQKEALDEQ 249

  Fly   345 TTKPKTNPNETSQKPKK--PTTKAAGETKAKT-EPDTDTD----------ISEQNPI------RQ 390
            ..:.|.:....| .||:  |....||||...: .|:...|          |:|.:.|      |.
 Frog   250 LIQFKESDRHLS-SPKRELPNASGAGETSDHSGSPEQQLDEKDARRFQLKIAELSSIIRKLEDRN 313

  Fly   391 AQVTPEITQL-----------------------KNIELI-------NNTKNAHKSALEMRTTMKS 425
            |.::.|..:|                       ||.|:.       |..|...:..:|||.....
 Frog   314 ALLSEERNELLKRLREAESQYKPILDKNKRLSRKNEEISHLLRRMENKLKFLTQENIEMRQKAGI 378

  Fly   426 SQPNGLDDAP----------TRMRAP------DEMRATTWMTTLVGSNCHSHS-----HSHPAVA 469
            .:|:.|:|..          .|::..      ||:..|......|.|......     .....:|
 Frog   379 RRPSSLNDLDQSREEREIDFLRLQLNEQQLFIDELCKTLETAGYVKSVLDREKLLRFRKQRKKMA 443

  Fly   470 KSKDP------NSDTDSALSSAPPSIS---------PQPPSSGSDSGVI--------------WQ 505
            |...|      ..|.:::|.|...|||         |..|....:.|:.              :|
 Frog   444 KLPKPVVETFFGYDEEASLDSDGSSISYHTDRTDRTPCTPDEDVEEGMAKEETELRFRQLTMEYQ 508

  Fly   506 TLQDLDKLQKE-------AEMYQKENERLQTEVQLMKQELDAAEKAAISRAKKQAQI-------- 555
            .||....|.:|       ||...|..|:||.::...::.::..|||...:.:....|
 Frog   509 ALQRAYALLQEQVGGTLDAEREVKTREQLQADIYQYQRTIEDLEKAMSEQGQDMKWIEEKQGLYR 573

  Fly   556 --GELMQRIKELEEMQSSLEDEASELREQNELLEFRILELEDDSDKM-------------ESTCE 605
              .||:.:||::|..::..:.:..::::|||||||||||||:...:.             :|..:
 Frog   574 RNQELVDKIKQMETDEAKFKHDIQDVKDQNELLEFRILELEERERRSPGITFHHIPFTEGKSPLQ 638

  Fly   606 GHCQS--LQDLLEQSAQRLEDRDKRCLQQLLQCVQQLDLDTMMPGDQNRTETPKRHNSTHSHSHS 668
            .:|::  :.|::                 :.:.:::||:   :..:.|.|
 Frog   639 VYCEAEGVTDII-----------------VSELMKKLDI---LGDNANLT--------------- 668

  Fly   669 HSHSQSHNHRIVATVQPYSNCATPTAPPTPSKRHCNQVSSW-QSSSLSESGVFV-------ECDL 725
                   |...|..:|              ::...|....| |...::||.:..       |.|.
 Frog   669 -------NDEQVIVIQ--------------ARTVLNLAEKWLQQIEVTESALQQKMVDLENEKDQ 712

  Fly   726 LSNPNPIGHPHLQFYQERLEQLEGKLLIYESSGETQARHLAQRLQRELQLEKDLKELADRVELLI 790
            .:.........|.|.::.|:|...::|..|:.       |...||:|:.        |....||.
 Frog   713 FTKQKGYLDDELDFRKQSLDQAHKQILELEAM-------LYDALQQEVG--------AKMAHLLS 762

  Fly   791 EQNAQLEEAKCEFEEAENDTRLHLQRNEVELEILRQRNVELEFGKEALGAKYQDCRAEVLILRED 855
            |:  :.||.||..|:.:....:.|:  |.:.:|||:|                         .|.
 Frog   763 EE--EREELKCAVEQWKRQVMIELR--ERDAQILRER-------------------------MEV 798

  Fly   856 LAAAETQLEHLQAERKQARKELQDLRRSLPLLLIFRLLSLA 896
            :..|:.:::.|:...:..:::|::|...  .|.:|...|||
 Frog   799 IQHAQQKIKELEERIEFQKRQLKELEEK--FLFLFLFFSLA 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pif1A	NP_001189195.2	JAKMIP_CC3	<516..595	CDD:464986	28/95 (29%)
		Smc	<741..>1156	CDD:440809	33/156 (21%)
jakmip3	XP_031762293.1	SMC_prok_B	27..819	CDD:274008	191/913 (21%)
		JAKMIP_CC3	428..623	CDD:464986	45/194 (23%)