DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr21 and dscama

DIOPT Version :9

Sequence 1:	NP_001163838.2	Gene:	dpr21 / 8674044	FlyBaseID:	FBgn0260995	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	251	Identity:	59/251 - (23%)
Similarity:	98/251 - (39%)	Gaps:	46/251 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LKETCP----QHFRENVT---------------VTDLYLISENIVPMKRVLDRGPYFDTSATKNV 61
            ||...|    ..||::||               |.:::....|...:.|:..:.|.....:.:.|
Zfish   260 LKNNRPLESDSRFRQSVTGLLIERAQPSDTGSYVCEVWNSYGNAEVIGRLTVKEPLKAVVSPRKV 324

  Fly    62 TSLVGITGHLNCRIKNLGNKTVSWIRHRDLHLLTVSESTYTSDQRFTSIYNKQTGDWSLQIKFPQ 126
            ...||....|:|.:.......:||.|:.|       :....::.|...| ||:    :|.:....
Zfish   325 KGSVGSQVSLSCSVTGSDEFELSWYRNGD-------KINTGANIRMNGI-NKE----NLVMDGMA 377

  Fly   127 LRDSGIYECQVSTTPPVGYTMVFSVVEPITSILGGPEI-------YIDLGSTVNLTCVIKHLPDP 184
            ..|.|:|:|............|..::|.     |.|:|       .:.....|:|||.:|..|.|
Zfish   378 KSDGGVYQCFSRKAKMSAQDFVQVILED-----GTPKILSAFSEKVVGPNDFVSLTCHVKGTPQP 437

  Fly   185 PISVQWNHNNQEINYDSPRGGVSVITEKGDITTSYLLIQRASIADSGQYTCLPSNA 240
            .|:  |..:::.:..||....|..||.:|:: .|||.|....:.|||.|.|..:|:
Zfish   438 AIT--WTLDDEVVAKDSRHRIVHSITAEGNV-VSYLNISHIQVRDSGVYRCTCNNS 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr21	NP_001163838.2	Ig	71..149	CDD:299845	15/77 (19%)
		IG_like	71..140	CDD:214653	15/68 (22%)
		IG_like	162..249	CDD:214653	27/86 (31%)
		IGc2	169..242	CDD:197706	25/72 (35%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352	10/50 (20%)
		IG_like	321..402	CDD:214653	19/92 (21%)
		I-set	408..502	CDD:333254	27/86 (31%)
		IGc2	524..579	CDD:197706
		Ig	614..679	CDD:319273
		Ig_DSCAM	708..787	CDD:143211
		Ig	805..898	CDD:325142
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910