DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr21 and NTM

DIOPT Version :9

Sequence 1:NP_001163838.2 Gene:dpr21 / 8674044 FlyBaseID:FBgn0260995 Length:282 Species:Drosophila melanogaster
Sequence 2:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens


Alignment Length:184 Identity:53/184 - (28%)
Similarity:81/184 - (44%) Gaps:20/184 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 ATKNVTSLVGITGHLNCRIKNLGNKTVSWIRHRDLHLLTVSESTYTSDQRFTSIYNKQTGDWSLQ 121
            |..|||...|.:..|.|.|.|...: |:|:....  :|......:..|.|...:.|.|| .:|::
Human    41 AMDNVTVRQGESATLRCTIDNRVTR-VAWLNRST--ILYAGNDKWCLDPRVVLLSNTQT-QYSIE 101

  Fly   122 IKFPQLRDSGIYECQVSTTPPVGYTMVFSVVEPITSILG-GPEIYIDLGSTVNLTCVIKHLPDPP 185
            |:...:.|.|.|.|.|.|......:.|..:|:....|:. ..:|.|:.|:.::|||:....|:| 
Human   102 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEP- 165

  Fly   186 ISVQWNHNNQEINYDSPRGGVSVITEKGDITTSYLLIQRASIADSGQYTCLPSN 239
             :|.|.|       .||: .|..::|     ..||.||..:...||.|.|..||
Human   166 -TVTWRH-------ISPK-AVGFVSE-----DEYLEIQGITREQSGDYECSASN 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr21NP_001163838.2 Ig 71..149 CDD:299845 20/77 (26%)
IG_like 71..140 CDD:214653 19/68 (28%)
IG_like 162..249 CDD:214653 25/78 (32%)
IGc2 169..242 CDD:197706 23/71 (32%)
NTMNP_001338930.1 Ig 44..132 CDD:416386 25/91 (27%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 2/3 (67%)
FR2 64..70 CDD:409353 2/6 (33%)
Ig strand C 64..70 CDD:409353 2/6 (33%)
CDR2 71..83 CDD:409353 1/13 (8%)
Ig strand C' 72..76 CDD:409353 0/5 (0%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 11/34 (32%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 1/5 (20%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 1/8 (13%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 136..205 CDD:404760 24/83 (29%)
Ig strand A' 142..147 CDD:409353 1/4 (25%)
Ig strand B 153..160 CDD:409353 3/6 (50%)
Ig strand C 166..171 CDD:409353 2/4 (50%)
Ig strand D 177..180 CDD:409353 1/2 (50%)
Ig strand E 184..190 CDD:409353 3/5 (60%)
Ig strand F 197..204 CDD:409353 3/6 (50%)
Ig strand G 211..219 CDD:409353
Ig_3 222..299 CDD:404760
putative Ig strand A 223..229 CDD:409353
Ig strand B 239..243 CDD:409353
Ig strand C 252..256 CDD:409353
Ig strand E 278..282 CDD:409353
Ig strand F 292..297 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.