DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr21 and Sdk2

DIOPT Version :9

Sequence 1:	NP_001163838.2	Gene:	dpr21 / 8674044	FlyBaseID:	FBgn0260995	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	XP_006247755.1	Gene:	Sdk2 / 360652	RGDID:	1310397	Length:	2175	Species:	Rattus norvegicus

Alignment Length:	245	Identity:	64/245 - (26%)
Similarity:	100/245 - (40%)	Gaps:	57/245 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FRENVTVT------------DLYLISENIVPMKR-----VLDRGPYFDTSATKNVTSLVGITGHL 71
            :...:|:|            :..|.|.::.|:.|     ||: .|.|.....:::|:.:.....:
  Rat   268 YNRRLTITNPMVSDAGYYECEAMLRSSSVAPVTRGAYLSVLE-PPQFVREPERHITAEMEKVVDI 331

  Fly    72 NCRIKNLGNKTVSWIRHRDLHLLTVSESTYTSDQRFTSIYNKQTGDWSLQIKFPQLRDSGIYEC- 135
            .||.|.:...:::|  ::|..|:.|.:.|     ||     ||..|..|||......|:|:.:|
  Rat   332 PCRAKGVPPPSITW--YKDAALVEVGKLT-----RF-----KQRSDGGLQISGLLPDDTGMVQCF 384

  Fly   136 --------QVSTTPPVGYTMVFSVVEPITSILGGP--EIYIDLGSTVNLTCVIKHLPDPPISVQW 190
                    |.||     |..|.|:...||.   ||  ...|| |.:|.|.|.....|.|.|:  |
  Rat   385 AHNAAGEAQTST-----YLAVTSIAPNITR---GPLDSTVID-GMSVVLACETSGAPRPAIT--W 438

  Fly   191 NHNNQEINYDSPRGGVSVITEKGDITTSYLLIQRASIADSGQYTCLPSNA 240
            ....:.:...|.:.....:.|.|.     |||....|:|:|.||||.:|:
  Rat   439 QKGERILASGSVQLPRFTLLESGS-----LLISPTHISDAGTYTCLATNS 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr21	NP_001163838.2	Ig	71..149	CDD:299845	23/86 (27%)
		IG_like	71..140	CDD:214653	21/77 (27%)
		IG_like	162..249	CDD:214653	25/81 (31%)
		IGc2	169..242	CDD:197706	22/72 (31%)
Sdk2	XP_006247755.1	IG_like	43..112	CDD:214653
		IGc2	43..101	CDD:197706
		IG_like	123..206	CDD:214653
		Ig	135..191	CDD:299845
		IG_like	225..307	CDD:214653	6/38 (16%)
		IGc2	236..289	CDD:197706	2/20 (10%)
		I-set	311..400	CDD:254352	26/105 (25%)
		Ig	329..397	CDD:143165	22/84 (26%)
		I-set	405..495	CDD:254352	28/90 (31%)
		Ig	419..495	CDD:299845	22/72 (31%)
		Ig	505..589	CDD:299845
		IG_like	505..589	CDD:214653
		FN3	593..684	CDD:238020
		FN3	696..789	CDD:238020
		FN3	797..893	CDD:238020
		FN3	898..986	CDD:238020
		FN3	996..1090	CDD:238020
		FN3	1102..1197	CDD:238020
		FN3	1204..1293	CDD:238020
		FN3	1304..1397	CDD:238020
		FN3	1403..1487	CDD:238020
		FN3	1506..1619	CDD:238020
		FN3	1629..1722	CDD:238020
		FN3	1727..1808	CDD:238020
		FN3	1840..1919	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910