DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr21 and Sdk1

DIOPT Version :9

Sequence 1:NP_001163838.2 Gene:dpr21 / 8674044 FlyBaseID:FBgn0260995 Length:282 Species:Drosophila melanogaster
Sequence 2:NP_808547.3 Gene:Sdk1 / 330222 MGIID:2444413 Length:2193 Species:Mus musculus


Alignment Length:240 Identity:58/240 - (24%)
Similarity:92/240 - (38%) Gaps:35/240 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 TDLYLISENIVPMKRVLDRGPYFDTSATKNVTSLVGITGHLNCRIKNLGNKTVSWIRHRDLHLLT 95
            |..||...||.|   ...:.| .||:.|.      |:|..|.|.:.......::|  .|..|:|.
Mouse   451 THTYLDVTNIAP---AFTQRP-VDTTVTD------GMTAVLRCEVSGAPKPAITW--KRGNHILA 503

  Fly    96 VSESTYTSDQRFTSIYNKQTGDWSLQIKFPQLRDSGIYECQVSTTPPVGYTMVFSVVEPITSILG 160
                  :...|.......::|  .|:|....::|:|.|.|..:.|...........|...|||:.
Mouse   504 ------SGSVRIPRFMLLESG--GLRIAPVFIQDAGNYTCYAANTEASVNASAMLTVWNRTSIVH 560

  Fly   161 GPEIYIDL-GSTVNLTCVIKHLPDPPISVQWNHNNQEINYDSPRGGVSVITEKGDITTSYLLIQR 224
            .||..:.: |:|..|.|...|.|...:...|..:|..|...|   ...::.||    ...|:|.:
Mouse   561 PPEDRVVIKGTTATLCCGATHDPRTSLRYVWKKDNVVITASS---SSRIVVEK----DGSLVISQ 618

  Fly   225 ASIADSGQYTC---LPSNANSKSVNVHILKGDHPAAVQKSHLLVS 266
            ....|.|.|||   ....::|::..:.:::..||    ..:||.|
Mouse   619 TWSGDIGDYTCEIISEGGSDSRTARLEVIELPHP----PQNLLAS 659

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr21NP_001163838.2 Ig 71..149 CDD:299845 15/77 (19%)
IG_like 71..140 CDD:214653 14/68 (21%)
IG_like 162..249 CDD:214653 22/90 (24%)
IGc2 169..242 CDD:197706 19/75 (25%)
Sdk1NP_808547.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56
Ig_2 94..169 CDD:290606
IG_like 100..169 CDD:214653
IG_like 183..263 CDD:214653
Ig 197..247 CDD:299845
IG_like 281..357 CDD:214653
IGc2 294..347 CDD:197706
I-set 368..457 CDD:254352 3/5 (60%)
Ig 388..454 CDD:143165 1/2 (50%)
I-set 462..552 CDD:254352 22/109 (20%)
Ig 476..552 CDD:299845 17/85 (20%)
I-set 557..646 CDD:254352 24/95 (25%)
Ig 562..646 CDD:299845 22/90 (24%)
FN3 650..741 CDD:238020 5/14 (36%)
fn3 753..839 CDD:278470
FN3 854..949 CDD:238020
FN3 954..1036 CDD:238020
FN3 1052..1148 CDD:238020
FN3 1158..1253 CDD:238020
FN3 1261..1349 CDD:238020
FN3 1360..1453 CDD:238020
FN3 1459..1554 CDD:238020
FN3 1562..1676 CDD:238020
FN3 1686..1779 CDD:238020
FN3 1784..1865 CDD:238020
FN3 1885..1978 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2057..2080
PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 2187..2193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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