DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42556 and tweek

DIOPT Version :9

Sequence 1:	NP_001162994.1	Gene:	CG42556 / 8674031	FlyBaseID:	FBgn0260758	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001286002.1	Gene:	tweek / 35026	FlyBaseID:	FBgn0261671	Length:	5150	Species:	Drosophila melanogaster

Alignment Length:	211	Identity:	46/211 - (21%)
Similarity:	75/211 - (35%)	Gaps:	58/211 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 FFDDLDDME-PEDEEGVMNHQYPILHSRHSDLFYMPNCVGPAYQGLISSLDQPYTTDCYMADEQT 99
            |.:|...|| |:.:||..:.:...:. |..|...:|..|   :...|.|..:.:..:..||::..
  Fly  3718 FEEDETQMESPDSDEGDQSCRDTFVR-RRGDFDNLPAFV---FDPTIDSKKRSFMMEKEMAEQLK 3778

  Fly   100 LVKENDSI---HDTI------LESLVAPTEMCVVAC--------------PKL---LLTYMRRLF 138
            ::.:..::   |:|:      |:.|.|       .|              |.|   |.||.|
  Fly  3779 IINDLRTLGASHNTVAHEERRLQELQA-------ICYKYFRRDMIQKWKRPSLRRSLKTYGR--- 3833

  Fly   139 QHPYARFGSSM----------NFSMIGLRFKDKDANKALTSF------VHFASYNSREIMDNGYW 187
            .|.|...|||:          |.|..|.|.....:|..::|.      .|..|.:.:.....|..
  Fly  3834 SHSYIGSGSSVSGVGVPQTLDNVSYTGRRLDTIASNDEISSLQSTPASCHSRSASLKHTTGGGVI 3898

  Fly   188 ADFINPLTGRAYYRAA 203
            ...:|.| ||..:..|
  Fly  3899 GGGVNAL-GRVTFTEA 3913

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42556	NP_001162994.1	DUF2246	<117..248	CDD:287231	27/120 (23%)
tweek	NP_001286002.1	FSA_C	4415..5113	CDD:287455
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3596
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900